Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
Vitamin D3 | 📋 | ✍ | ⛔ | | 38715063 | Causal association between low vitamin D and polycystic ovary syndrome: a bidirectional mendelian randomization study |
Curcumin | 📋 | ✍ | ⛔ | | 38576560 | Transcriptomics and metabonomics study on the effect of exercise combined with curcumin supplementation on breast cancer in mice |
Melatonin | 📋 | ✍ | ⛔ | | 38692429 | Exploring melatonin's multifaceted role in female reproductive health: From follicular development to lactation and its therapeutic potential in obstetric syndromes |
Resveratrol | 📋 | ✍ | ⛔ | | 38622741 | The impact of resveratrol on the outcome of the in vitro fertilization: an exploratory randomized placebo-controlled trial |
Metformin | 📋 | ✍ | ⛔ | | 38677349 | Metformin inhibits activation of NLRP3 inflammasome and inflammatory response in preeclamptic rats |
Ginsenosides | 📋 | ✍ | ⛔ | | 38455405 | Ginsenoside Rg3 decreases breast cancer stem-like phenotypes through impairing MYC mRNA stability |
Quercetin | 📋 | ✍ | ⛔ | | 38714236 | Quercetin exerts anti-tumor immune mechanism by regulating IL-6/JAK2/STAT3 signaling pathway to deplete Treg cells |
Berberine | 📋 | ✍ | ⛔ | | 38709912 | Berberine inhibits the progression of breast cancer by regulating METTL3-mediated m6A modification of FGF7 mRNA |
Genistein | 📋 | ✍ | ⛔ | | 38304042 | Genistein Ameliorated Vascular Endothelial Growth Factor-A (VEGF-A) and Estrogen Receptor-Alpha (ER- α) in Endometriosis Mice Model, In Vivo and In Silico |
EGCG | 📋 | ✍ | ⛔ | | 38398883 | Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases-Focus on Epigenetic Mechanisms |
Vitamin C | 📋 | ✍ | ⛔ | | 37836389 | Effects of Low Vitamin C Intake on Fertility Parameters and Pregnancy Outcomes in Guinea Pigs |
Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38628754 | Effect of omega-3 supplements or diets on fertility in women: A meta-analysis |
Vitamin E | 📋 | ✍ | ⛔ | | 38408971 | Effect of vitamin E with and without saffron on the sexual function in women of reproductive age with sexual dysfunction: a randomized controlled trial |
Sulforaphane | 📋 | ✍ | ⛔ | | 38438062 | Sulforaphane's role in Redefining autophagic Responses in depression associated with polycystic ovarian syndrome: Unveiling the SIRT1/AMPK/LKB1 pathway connection |
Selenium | 📋 | ✍ | ⛔ | | 38720217 | Selenium Supplementation and Gestational Diabetes: A Randomised Controlled Trial |
Vitamin B8 | 📋 | ✍ | ⛔ | | 38674244 | Dietary Supplementation of Myo-Inositol, Cocoa Polyphenols, and Soy Isoflavones Improves Vasomotor Symptoms and Metabolic Profile in Menopausal Women with Metabolic Syndrome: A Retrospective Clinical Study |
Luteolin | 📋 | ✍ | ⛔ | | 38705425 | Luteolin and its analog luteolin-7-methylether from Leonurus japonicus Houtt suppress aromatase-mediated estrogen biosynthesis to alleviate polycystic ovary syndrome by the inhibition of tumor progression locus 2 |
Micronutrients | 📋 | | ⛔ | | 38542717 | Empowering Strategies for Lifestyle Interventions, Diet Modifications, and Environmental Practices for Uterine Fibroid Prevention; Unveiling the LIFE UP Awareness |
DHEA | 📋 | ✍ | ⛔ | | 38494723 | Dehydroepiandrosterone modulates the PTEN/PI3K/AKT signaling pathway to alleviate 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency in rats |
Apigenin | 📋 | ✍ | ⛔ | | 38664447 | Apigenin and its combination with Vorinostat induces apoptotic-mediated cell death in TNBC by modulating the epigenetic and apoptotic regulators and related miRNAs |
Magnesium | 📋 | ✍ | ⛔ | | 38128389 | The efficacy of magnesium supplementation for gestational diabetes: A meta-analysis of randomized controlled trials |
Medicinal Plants | 📋 | | | | 38312763 | Role of Alternate Therapies to Improve the Quality of Life in Menopausal Women: A Systematic Review |
Thymoquinone | 📋 | | ⛔ | | 38446390 | Computational and in vitro analyses on synergistic effects of paclitaxel and thymoquinone in suppressing invasive breast cancer cells |
Aspirin | 📋 | | ⛔ | | 38466003 | Protective Effects of Aspirin Supplemented With Quercetin in L-NAME-Induced Preeclampsia-Like Rats |
Cannabidiol | 📋 | ✍ | ⛔ | | 38603577 | Cannabidiol Inhibits Epithelial Ovarian Cancer: Role of Gut Microbiome |
Naringenin | 📋 | ✍ | ⛔ | | 38253629 | Network pharmacology combined with experimental verification to explore the potential mechanism of naringenin in the treatment of cervical cancer |
Pterostilbene | 📋 | ✍ | ⛔ | | 38296018 | Pterostilbene upregulates MICA/B via the PI3K/AKT signaling pathway to enhance the capability of natural killer cells to kill cervical cancer cells |
Baicalein | 📋 | ✍ | ⛔ | | 38607237 | Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling |
Lipoic Acid | 📋 | ✍ | ⛔ | | 38699871 | Alpha-Lipoic Acid Induces Adipose Tissue Browning through AMP-Activated Protein Kinase Signaling in Vivo and in Vitro |
Withaferin A | 📋 | | | | 38525814 | Withaferin A alters the expression of microRNAs 146a-5p and 34a-5p and associated hub genes in MDA-MB-231 cells |
Astaxanthin | 📋 | ✍ | ⛔ | | 38638038 | Astaxanthin as an Anticancer Agent against Breast Cancer: An In Vivo and In Vitro Investigation |
CoQ10 | 📋 | ✍ | ⛔ | | 37667786 | Coenzyme Q10 Stimulate Reproductive Vatality |
Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 38439112 | Docosahexaenoic acid (DHA) impairs hypoxia-induced cellular and exosomal overexpression of immune-checkpoints and immunomodulatory molecules in different subtypes of breast cancer cells |
Fisetin | 📋 | ✍ | ⛔ | | 37480513 | Naringenin in combination with quercetin/fisetin shows synergistic anti-proliferative and migration reduction effects in breast cancer cell lines |
N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 37841396 | The effects of N-acetylcysteine supplement on metabolic parameters in women with polycystic ovary syndrome: a systematic review and meta-analysis |
Phytochemicals | 📋 | | | | 38723515 | Natural products as glycolytic inhibitors for cervical cancer treatment: A comprehensive review |
Pomegranate | 📋 | | ⛔ | | 36654481 | The effect of concentrated pomegranate juice on biomarkers of inflammation, oxidative stress, and sex hormones in overweight and obese women with polycystic ovary syndrome: A randomized controlled trial |
Reishi Mushrooms | 📋 | ✍ | ⛔ | | 38599178 | Ganoderma lucidum and Hypericum perforatum exhibit anti-inflammatory, antioxidant and anti-androgen effect in rat model of experimental polycystic ovarian syndrome |
Ellagic Acid | 📋 | ✍ | ⛔ | | 38476024 | CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A |
Nigella Sativa | 📋 | ✍ | ⛔ | | 38578469 | Determination of anti-cancer effects of Nigella sativa seed oil on MCF7 breast and AGS gastric cancer cells |
Silibinin | 📋 | ✍ | | | 38643945 | Inhibition of YAP/TAZ pathway contributes to the cytotoxicity of silibinin in MCF-7 and MDA-MB-231 human breast cancer cells |
Probiotics | 📋 | ✍ | ⛔ | | 38463778 | Vaginal microbiota: Potential targets for vulvovaginal candidiasis infection |
Vitamin B9 | 📋 | ✍ | ⛔ | | 37818092 | Enhanced recovery in patients with gestational diabetes mellitus and MTHFR 677 TT genotype after taking high-dose folic acid supplements during mid-late pregnancy: an open-label interventional study |
Evening Primrose Oil | 📋 | ✍ | ⛔ | | 38377980 | The Use of Evening Primrose Oil for Cervical Ripening in Low-Risk Women with Term Pregnancy: A Randomized Double-Blinded Controlled Trial |
Progesterone | 📋 | ✍ | ⛔ | | 38415405 | Progesterone inhibits endometrial cancer growth by inhibiting glutamine metabolism through ASCT2 |
Soy Isoflavones | 📋 | ✍ | ⛔ | | 38674244 | Dietary Supplementation of Myo-Inositol, Cocoa Polyphenols, and Soy Isoflavones Improves Vasomotor Symptoms and Metabolic Profile in Menopausal Women with Metabolic Syndrome: A Retrospective Clinical Study |
Tribulus Terrestris | 📋 | ✍ | ⛔ | | 37639811 | Tribulus terrestris L. induces cell apoptosis of breast cancer by regulating sphingolipid metabolism signaling pathways |
Bee Propolis | 📋 | ✍ | ⛔ | | 38473725 | Biological Activity and Chemical Composition of Propolis Extracts with Potential Use in Vulvovaginal Candidiasis Management |
Crocin | 📋 | ✍ | ⛔ | | 38661582 | Crocin enhances the sensitivity to paclitaxel in human breast cancer cells by reducing BIRC5 expression |
Gallic Acid | 📋 | | ⛔ | | 38553133 | Gallic acid ameliorates endometrial hyperplasia through the inhibition of the PI3K/AKT pathway and the down-regulation of cyclin D1 expression |
Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 38201092 | Comparative Anticancer Potential of Green Tea Extract and Epigallocatechin-3-gallate on Breast Cancer Spheroids |
Lycopene | 📋 | ✍ | ⛔ | | 37429407 | Protective effects of lycopene against zearalenone-induced reproductive toxicity in early pregnancy through anti-inflammatory, antioxidant and anti-apoptotic effects |
Fucoidan | 📋 | ✍ | ⛔ | | 38567646 | Fucoidan extract from brown seaweed (Sargassum echinocarpum): molecular weight, elemental composition, selectivity and anticancer activity against breast cancer cells |
Baicalin | 📋 | ✍ | ⛔ | | 38430630 | Exploring MTH1 inhibitory potential of Thymoquinone and Baicalin for therapeutic targeting of breast cancer |
Ginger | 📋 | ✍ | ⛔ | | 38671840 | Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome (PCOS) and Other Oxidative Stress-Related Disorders |
Kaempferol | 📋 | ✍ | ⛔ | | 38062663 | Exploration of the Mechanism of Kaempferol in the Treatment of Cervical Cancer-based on Metabolomics and Network Pharmacology |
Piperine | 📋 | ✍ | ⛔ | | 38233443 | Synergistic effects of bee venom, hesperidin, and piperine with tamoxifen on apoptotic and angiogenesis biomarker molecules against xerographic MCF-7 injected rats |
Zinc | 📋 | ✍ | ⛔ | | 37165643 | Efficacy of zinc supplementation for the treatment of dysmenorrhoea: a double-blind randomised controlled trial |
Chrysin | 📋 | ✍ | ⛔ | | 38110365 | Pyrotinib and chrysin synergistically potentiate autophagy in HER2-positive breast cancer |
Daidzein | 📋 | ✍ | ⛔ | | 37909594 | Effects of daidzein on rat ovary against ischemia-reperfusion |
Emodin | 📋 | | ⛔ | | 37821408 | Emodin reduces surgical wounding-accelerated tumor growth and metastasis via macrophage suppression in a murine triple-negative breast cancer model |
Ginseng | 📋 | ✍ | ⛔ | | 37175917 | Red Ginseng Improves D-galactose-Induced Premature Ovarian Failure in Mice Based on Network Pharmacology |
Cinnamon | 📋 | ✍ | ⛔ | | 38671840 | Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome (PCOS) and Other Oxidative Stress-Related Disorders |
Food | 📋 | | | | 38715795 | Mendelian randomization reveals the impact of diet on infertility in men and women |
Gingerol | 📋 | ✍ | | | 37900164 | 6-Gingerol alleviates placental injury in preeclampsia by inhibiting oxidative stress via BNIP3/LC3 signaling-mediated trophoblast mitophagy |
Licorice Root | 📋 | ✍ | ⛔ | | 37580936 | Ameliorative effects of a Chinese herbal formula, fufang meidengmu on uterine leiomyoma in a mice model |
Tanshinone | 📋 | | | | 38615741 | Tanshinone IIA destabilizes SLC7A11 by regulating PIAS4-mediated SUMOylation of SLC7A11 through KDM1A, and promotes ferroptosis in breast cancer |
Astragalosides | 📋 | ✍ | ⛔ | | 38193000 | Astragaloside IV enhances the sensitivity of breast cancer stem cells to paclitaxel by inhibiting stemness |
Chamomile | 📋 | ✍ | ⛔ | | 37465426 | Examining the Effect of Chamomile on Clinical Symptoms and Hormonal Parameters Among Patients With Polycystic Ovarian Syndrome |
Hesperidin | 📋 | ✍ | ⛔ | | 38233443 | Synergistic effects of bee venom, hesperidin, and piperine with tamoxifen on apoptotic and angiogenesis biomarker molecules against xerographic MCF-7 injected rats |
Phytoestrogens | 📋 | | ⛔ | | 38375679 | Dietary phytoestrogen intake and ovarian cancer risk: a prospective study in the Prostate, Lung, Colorectal and Ovarian (PLCO) cohort |
Puerarin | 📋 | ✍ | ⛔ | | 38305024 | Puerarin Ameliorated PCOS through Preventing Mitochondrial Dysfunction Dependent on the Maintenance of Intracellular Calcium Homeostasis |
Saffron | 📋 | ✍ | ⛔ | | 38694315 | Saffron extract as an emerging novel therapeutic option in reproduction and sexual health: recent advances and future prospectives |
Andrographolide | 📋 | | | | 36352155 | Andrographolide elevates tumor necrosis factor-related apoptosis-inducing ligand lethality through reactive oxygen species accumulation and gasdermin E cleavage in breast cancer cells |
Ginkgo Biloba | 📋 | ✍ | ⛔ | | 35285758 | Ginkgo biloba extract 761 reduces vascular permeability of the ovary and improves the symptom of ovarian hyperstimulation syndrome in a rat model |
Hyaluronic Acid | 📋 | ✍ | ⛔ | | 38468593 | Prospective, multicenter, uncontrolled study on the effectiveness and safety of a hyaluronic acid water-based vaginal lubricant in alleviating vaginal dryness and dyspareunia |
Rutin | 📋 | ✍ | ⛔ | | 38404048 | Positive effects of rutin on female reproduction |
Green Tea | 📋 | ✍ | ⛔ | | 37637856 | Prevention of Uterine Fibroids: molecular mechanisms and potential clinical application |
Hesperetin | 📋 | | | | 38462023 | Investigating the effect of hesperetin on estrogen receptor alpha (ERα) expression, phosphorylation and activity in MCF-7 cells |
Moringa Oleifera | 📋 | ✍ | ⛔ | | 38543016 | Phytochemical Profiling by UHPLC-Q-TOF/MS and Chemopreventive Effect of Aqueous Extract of Moringa oleifera Leaves and Benzyl Isothiocyanate on Murine Mammary Carcinogenesis |
Wogonin | 📋 | ✍ | ⛔ | | 37910344 | Wogonin attenuates inflammation and oxidative stress in lipopolysaccharide-induced mastitis by inhibiting Akt/NF-κB pathway and activating the Nrf2/HO-1 signaling |
Dihydromyricetin | 📋 | ✍ | ⛔ | | 36692465 | Ampelopsin induces MDA-MB-231 cell cycle arrest through cyclin B1-mediated PI3K/AKT/mTOR pathway in vitro and in vivo |
Fennel | 📋 | ✍ | ⛔ | | 37694196 | Comparison of the Effect of Fennel and Evening Primrose Oil on Menopausal Problems and Hormonal Levels: A Randomized Controlled Trial |
Formononetin | 📋 | | | | 38531802 | Formononetin Restrains Tumorigenesis of Breast Tumor by Restraining STING-NF-κB and Interfering with the Activation of PD-L1 |
Grape Seed extract | 📋 | ✍ | ⛔ | | 38398737 | Antioxidant and Anticancer Activity of Vitis vinifera Extracts in Breast Cell Lines |
Icariin | 📋 | ✍ | | | 38355608 | Icariin exerts anti-tumor activity by inducing autophagy via AMPK/mTOR/ULK1 pathway in triple-negative breast cancer |
L-Arginine | 📋 | ✍ | ⛔ | | 37466772 | Pathophysiology of Preeclampsia and L-Arginine/L-Citrulline Supplementation as a Potential Strategy to Improve Birth Outcomes |
Nobiletin | 📋 | ✍ | | | 38721626 | Nobiletin Inhibits Breast Cancer Stem Cell by Regulating the Cell Cycle: A Comprehensive Bioinformatics Analysis and In Vitro Experiments |
Oleuropein | 📋 | | | | 38629155 | Novel Anti-tumor Strategy for Breast Cancer: Synergistic Role of Oleuropein with Paclitaxel Therapeutic in MCF-7 Cells |
Beta-Carotene | 📋 | ✍ | ⛔ | | 37270031 | β-carotene targets IP3R/GRP75/VDAC1-MCU axis to renovate LPS-induced mitochondrial oxidative damage by regulating STIM1 |
Black Cohosh | 📋 | ✍ | ⛔ | | 38139334 | In Vitro and In Vivo Imaging-Based Evaluation of Doxorubicin Anticancer Treatment in Combination with the Herbal Medicine Black Cohosh |
Chlorogenic Acid | 📋 | ✍ | ⛔ | | 38543147 | Natural Compounds and Breast Cancer: Chemo-Preventive and Therapeutic Capabilities of Chlorogenic Acid and Cinnamaldehyde |
Fenugreek | 📋 | ✍ | ⛔ | | 38000191 | Unraveling the mechanisms of Fenugreek seed for managing different gynecological disorders: steroidal saponins and isoflavones revealed as key bioactive metabolites |
Graviola | 📋 | ✍ | ⛔ | | 38708435 | Untargeted metabolomics using UHPLC-Q-Orbitrap HRMS for identifying cytotoxic compounds on MCF-7 breast cancer cells from Annona muricata Linn leaf extracts as potential anticancer agents |
Hydroxytyrosol | 📋 | | | | 38518601 | Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells |
L-Carnitine | 📋 | ✍ | ⛔ | | 37863343 | The effect of L-carnitine on oocyte mitochondrial health and biomarkers on cyclophosphamide chemotherapy drug in mice |
NMN | 📋 | ✍ | ⛔ | | 38684562 | Nicotinamide Mononucleotide and Nicotinamide Riboside Reverse Ovarian Aging in Rats Via Rebalancing Mitochondrial Fission and Fusion Mechanisms |
Olive Oil | 📋 | ✍ | ⛔ | | 38084993 | Synergistic Action of Virgin Coconut Oil and Clomiphene in Reversing Endocrine Dysregulation in Letrozole-Model of Polycystic Ovarian Syndrome in Rats: Role of Nrf2/HMOX-1 Pathway |
Soy | 📋 | ✍ | ⛔ | | 38474777 | Royal Jelly and Fermented Soy Extracts-A Holistic Approach to Menopausal Symptoms That Increase the Quality of Life in Pre- and Post-menopausal Women: An Observational Study |
Aloe-Emodin | 📋 | | | | 36430215 | Cell Metabolomics Reveals the Potential Mechanism of Aloe Emodin and Emodin Inhibiting Breast Cancer Metastasis |
Arctigenin | 📋 | | | | 37492896 | Combined doxorubicin and arctigenin treatment induce cell cycle arrest-associated cell death by promoting doxorubicin uptake in doxorubicin-resistant breast cancer cells |
Calcium | 📋 | ✍ | ⛔ | | 38406773 | The effects of vitamin D and calcium on primary dysmenorrhea: a systematic review |
Carotenoids | 📋 | ✍ | ⛔ | | 38166673 | Association between serum carotenoids and bacterial vaginosis infection among American women |
Dandelion | 📋 | ✍ | ⛔ | | 37814658 | Hydroalcoholic extract of Taraxacum officinale induces apoptosis and autophagy in 4T1 breast cancer cells |
Honokiol | 📋 | | | | 38576101 | Honokiol regulates ovarian cancer cell malignant behavior through YAP/TAZ pathway modulation |
Isoflavones | 📋 | ✍ | ⛔ | | 38590945 | Activity of isoflavone in managing polycystic ovary syndrome symptoms (Review) |
Vitamin B12 | 📋 | ✍ | ⛔ | | 37674548 | Micronutrients and prevention of cervical pre-cancer in HPV vaccinated women: a cross-sectional study |
Aloe Vera | 📋 | ✍ | ⛔ | | 38529934 | Effects of Aloe Gel on Lactating Women with Nipple Trauma |
Fucoxanthin | 📋 | ✍ | ⛔ | | 38202644 | The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells |
Garlic | 📋 | ✍ | ⛔ | | 38546072 | Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It |
Goji Berry | 📋 | ✍ | ⛔ | | 38280710 | Specific molecular weight of Lycium barbarum polysaccharide for robust breast cancer regression by repolarizing tumor-associated macrophages |
Sage | 📋 | ✍ | ⛔ | | 38464730 | Salvia officinalis L. exerts oncostatic effects in rodent and in vitro models of breast carcinoma |
Skullcap | 📋 | ✍ | ⛔ | | 38525246 | Scutellaria barbata D.Don extract regulates Ezrin-mediated triple negative breast cancer progress via suppressing the RhoA /ROCK1 signaling |
Vitamin A | 📋 | ✍ | ⛔ | | 38226115 | Vitamin A-Mediated Birth Defects: A Narrative Review |
Vitex | 📋 | ✍ | ⛔ | | 38393671 | Use of Vitex agnus-castus in patients with menstrual cycle disorders: a single-center retrospective longitudinal cohort study |
Ashwagandha | 📋 | ✍ | ⛔ | | 38685363 | Molecular Mechanisms of Asparagus racemosus Willd. and Withania somnifera (L.) Dunal as Chemotherapeutic Adjuvants for Breast Cancer Treatment |
Eugenol | 📋 | | | | 36923216 | Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells |
Fish Oil | 📋 | ✍ | ⛔ | | 37081029 | Anti-inflammatory effect of combining fish oil and evening primrose oil supplementation on breast cancer patients undergoing chemotherapy: a randomized placebo-controlled trial |
Flaxseed | 📋 | ✍ | ⛔ | | 38063410 | The efficacy of Linum usitatissimum seeds to inhibit estrogen receptor as a natural therapy for PCOS: An in silico and in vitro analysis |
Frankincense | 📋 | ✍ | ⛔ | | 38194131 | The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer |
Myricetin | 📋 | | ⛔ | | 38520750 | Myricetin ameliorates polycystic ovary syndrome in mice by brown adipose tissue activation |
Retinoic Acid | 📋 | | | | 37700002 | Combined dandelion extract and all-trans retinoic acid induces cytotoxicity in human breast cancer cells |
Stinging Nettle | 📋 | ✍ | ⛔ | | 37806999 | Identification of novel inhibitors from Urtica spp against TNBC targeting JAK2 receptor for breast cancer therapy |
Vitamin B6 | 📋 | ✍ | ⛔ | | 37736936 | Effect of Oral High Molecular Weight Hyaluronic Acid (HMWHA), Alpha Lipoic Acid (ALA), Magnesium, Vitamin B6 and Vitamin D Supplementation in Pregnant Women: A Retrospective Observational Pilot Study |
Amygdalin | 📋 | ✍ | ⛔ | | 36732462 | Docking and Molecular Dynamics Simulation Revealed the Potential Inhibitory Activity of Amygdalin in Triple-Negative Breast Cancer Therapeutics Targeting the BRCT Domain of BARD1 Receptor |
Astragalus Root | 📋 | ✍ | ⛔ | | 37824046 | Astragalus polysaccharide alleviates polycystic ovary syndrome by reducing insulin resistance and oxidative stress and increasing the diversity of gut microbiota |
Boric Acid | 📋 | ✍ | ⛔ | | 38087035 | Boric Acid Alters the Expression of DNA Double Break Repair Genes in MCF-7-Derived Breast Cancer Stem Cells |
Boswellic Acid | 📋 | ✍ | ⛔ | | 35712503 | β-Boswellic Acid Suppresses Breast Precancerous Lesions via GLUT1 Targeting-Mediated Glycolysis Inhibition and AMPK Pathway Activation |
CAPE | 📋 | | | | 37786469 | Caffeic Acid Phenethyl Ester Reduces the Adverse Effects of Nicotine on the Endometrium |
Cocoa | 📋 | ✍ | ⛔ | | 38674244 | Dietary Supplementation of Myo-Inositol, Cocoa Polyphenols, and Soy Isoflavones Improves Vasomotor Symptoms and Metabolic Profile in Menopausal Women with Metabolic Syndrome: A Retrospective Clinical Study |
Coffee | 📋 | ✍ | ⛔ | | 36381474 | The Effect of Green Coffee Supplementation on Lipid Profile, Glycemic Indices, Inflammatory Biomarkers and Anthropometric Indices in Iranian Women With Polycystic Ovary Syndrome: A Randomized Clinical Trial |
Folate | 📋 | ✍ | ⛔ | | 37468843 | Negative associations between folate and bacterial vaginosis in the NHANES 2001 to 2004 |
Kacip Fatimah | 📋 | ✍ | ⛔ | | 34568497 | A Review on Therapeutic Effects of Labisia pumila on Female Reproductive Diseases |
Licochalcones | 📋 | | | | 38308464 | Licochalcone A induces endoplasmic reticulum stress-mediated apoptosis of endometrial cancer cells via upregulation of GRP78 expression |
Pomegranate Peel extract | 📋 | ✍ | ⛔ | | 38027211 | Modulatory effect of pomegranate peel extract on key regulators of ovarian cellular processes in vitro |
Ursolic Acid | 📋 | ✍ | ⛔ | | 37992132 | Ursolic acid regulates key EMT transcription factors, induces cell cycle arrest and apoptosis in MDA-MB-231 and MCF-7 breast cancer cells, an in-vitro and in silico studies |
Allicin | 📋 | ✍ | ⛔ | | 38628206 | Allicin inhibits the biological activities of cervical cancer cells by suppressing circEIF4G2 |
Apple | 📋 | | ⛔ | | 32064624 | Phytochemical profiles, antioxidant, and antiproliferative activities of four red-fleshed apple varieties in China |
Bee Venom | 📋 | ✍ | ⛔ | | 38533165 | Bee Sting Venom as a Viable Therapy for Breast Cancer: A Review Article |
Diallyl Trisulfide | 📋 | | | | 38276538 | The Garlic Compound, Diallyl Trisulfide, Attenuates Benzo[a]Pyrene-Induced Precancerous Effect through Its Antioxidant Effect, AhR Inhibition, and Increased DNA Repair in Human Breast Epithelial Cells |
Fig | 📋 | | ⛔ | | 38139849 | Regulatory Effect of Ficus carica Latex on Cell Cycle Progression in Human Papillomavirus-Positive Cervical Cancer Cell Lines: Insights from Gene Expression Analysis |
Ginger extract | 📋 | ✍ | ⛔ | | 33907432 | Coadministration of Ginger Extract and Fluconazole Shows a Synergistic Effect in the Treatment of Drug-Resistant Vulvovaginal Candidiasis |
Red Sage | 📋 | ✍ | ⛔ | | 38678618 | Research progress on the mechanism of action of Salvia miltiorrhiza and its components in the treatment of endometrial carcinoma |
Tangeretin | 📋 | | | | 34335799 | Integrative Bioinformatics Study of Tangeretin Potential Targets for Preventing Metastatic Breast Cancer |
Walnut | 📋 | | ⛔ | | 33110438 | Beneficial effects of walnut ( Juglans regia L.) oil-derived polyunsaturated fatty acid prevents a prooxidant status and hyperlipidemia in pregnant rats with diabetes |
Wormwood | 📋 | ✍ | ⛔ | | 38405483 | Identifying the Main Components and Mechanisms of Action of Artemisia annua L. in the Treatment of Endometrial Cancer Using Network Pharmacology |
Anthocyanins | 📋 | ✍ | ⛔ | | 37190229 | Anthocyanins Reduce Cell Invasion and Migration through Akt/mTOR Downregulation and Apoptosis Activation in Triple-Negative Breast Cancer Cells: A Systematic Review and Meta-Analysis |
Asafoetida | 📋 | ✍ | ⛔ | | 37655000 | "Ferula assa-foetida L" or "Foeniculum vulgare"? Which one is more effective in the management of polycystic ovarian syndrome? A randomized, placebo controlled, triple-blinded |
Butyrate | 📋 | | ⛔ | | 38507924 | Specific vaginal and gut microbiome and the anti-tumor effect of butyrate in cervical cancer women |
Carvacrol | 📋 | ✍ | ⛔ | | 36965892 | The effect of carvacrol on the proinflammatory cytokines, histology, and fertility outcome of cisplatin-related ovarian change in a rat model |
Cinnamaldehyde | 📋 | | | | 38543147 | Natural Compounds and Breast Cancer: Chemo-Preventive and Therapeutic Capabilities of Chlorogenic Acid and Cinnamaldehyde |
Flavonoids | 📋 | | ⛔ | | 38403145 | Evaluating flavonoids as potential aromatase inhibitors for breast cancer treatment: In vitro studies and in silico predictions |
Glycyrrhizic Acid | 📋 | ✍ | ⛔ | | 37659683 | Glycyrrhizic acid enhances the anticancer activity of cisplatin in the human ovarian cancer cell line |
Kudzu Root | 📋 | ✍ | ⛔ | | 36501055 | Puerariae lobatae Radix Alleviates Pre-Eclampsia by Remodeling Gut Microbiota and Protecting the Gut and Placental Barriers |
Lutein | 📋 | ✍ | ⛔ | | 34084220 | Long non-coding RNA CASC9/microRNA-590-3p axis participates in lutein-mediated suppression of breast cancer cell proliferation |
Punicalagin | 📋 | ✍ | ⛔ | | 38329023 | Punicalagin improves inflammation and oxidative stress in rat model of pelvic inflammatory disease |
Theaflavins | 📋 | ✍ | | | 34601223 | Epigallocatechin gallate and theaflavins independently alleviate cyclophosphamide-induced ovarian damage by inhibiting the overactivation of primordial follicles and follicular atresia |
Turmeric | 📋 | ✍ | ⛔ | | 37373663 | Effect of Turmeric-Boswellia-Sesame Formulation in Menstrual Cramp Pain Associated with Primary Dysmenorrhea-A Double-Blind, Randomized, Placebo-Controlled Study |
Acetyl-L-Carnitine | 📋 | ✍ | ⛔ | | 37760915 | Acyl-Carnitines Exert Positive Effects on Mitochondrial Activity under Oxidative Stress in Mouse Oocytes: A Potential Mechanism Underlying Carnitine Efficacy on PCOS |
Angelica | 📋 | ✍ | ⛔ | | 38703506 | Angelica sinensis polysaccharide combined with cisplatin reverses cisplatin resistance of ovarian cancer by inducing ferroptosis via regulating GPX4 |
Catechins | 📋 | | | | 34281228 | Co-Adjuvant Therapy Efficacy of Catechin and Procyanidin B2 with Docetaxel on Hormone-Related Cancers In Vitro |
Crocetin | 📋 | | | | 34851635 | Crocetin Alleviates Ovariectomy-Induced Metabolic Dysfunction through Regulating Estrogen Receptor β |
Grape | 📋 | | ⛔ | | 37260897 | Antioxidant capacity and cytotoxic effect of an optimized extract of isabella grape ( Vitis labrusca) on breast cancer cells |
Isoliquiritigenin | 📋 | | | | 32736296 | The effects of isoliquiritigenin on endometriosis in vivo and in vitro study |
Maitake Mushrooms | 📋 | | ⛔ | | 38169590 | Polysaccharide isolated from Grifola frondosa eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses |
Naringin | 📋 | ✍ | ⛔ | | 38310190 | Combined effects of naringin and doxorubicin on the JAK/STAT signaling pathway reduce the development and spread of breast cancer cells |
Paeonol | 📋 | | | | 38493906 | Paeonol alleviates postmenopause-induced neuropsychiatric symptoms through the modulation of GPR30 in ovariectomized mice |
Polyphenols | 📋 | | | | 38539230 | Role of polyphenols in remodeling the host gut microbiota in polycystic ovary syndrome |
Procyanidins | 📋 | | ⛔ | | 37515969 | Procyanidin B2 alleviates uterine toxicity induced by cadmium exposure in rats: The effect of oxidative stress, inflammation, and gut microbiota |
Raspberry | 📋 | ✍ | ⛔ | | 38398530 | The Effect of Rubus idaeus Polyphenols Extract in Induced Endometriosis in Rats |
Rosmarinic Acid | 📋 | ✍ | | | 38201832 | Molecular Pathways of Rosmarinic Acid Anticancer Activity in Triple-Negative Breast Cancer Cells: A Literature Review |
Royal Jelly | 📋 | ✍ | ⛔ | | 38717683 | Royal jelly and its hormonal effects in breast cancer: a literature review |
Salidroside | 📋 | | | | 38641312 | Salidroside prevents gestational hypertension-induced impairment of offspring learning and memory via Wnt/Skp2 pathway |
Valerian Root | 📋 | ✍ | ⛔ | | 37160299 | Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
Vitamins | 📋 | | | | 38029770 | The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility |
Acai Berry | 📋 | ✍ | ⛔ | | 34884824 | Increased Systemic Antioxidant Power Ameliorates the Aging-Related Reduction in Oocyte Competence in Mice |
Beta-Sitosterol | 📋 | ✍ | ⛔ | | 38364944 | β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer |
Betaine | 📋 | ✍ | ⛔ | | 38488483 | Betaine postpones hyperglycemia-related senescence in ovarian and testicular cells: Involvement of RAGE and β-galactosidase |
Biochanin A | 📋 | | | | 37289419 | An Insight on Synergistic Anti-cancer Efficacy of Biochanin A and Sulforaphane Combination Against Breast Cancer |
Blueberry | 📋 | ✍ | ⛔ | | 34439566 | Dietary Blueberry and Soluble Fiber Improve Serum Antioxidant and Adipokine Biomarkers and Lipid Peroxidation in Pregnant Women with Obesity and at Risk for Gestational Diabetes |
Carnosic Acid | 📋 | | | | 30558262 | Carnosic Acid Modulates Increased Hepatic Lipogenesis and Adipocytes Differentiation in Ovariectomized Mice Fed Normal or High-Fat Diets |
Cryptotanshinone | 📋 | | | | 38039759 | Cryptotanshinone suppresses ovarian cancer via simultaneous inhibition of glycolysis and oxidative phosphorylation |
Dihydroquercetin | 📋 | | | | 37394519 | Unveiling the multitargeted repurposing potential of taxifolin (dihydroquercetin) in cervical cancer: an extensive MMGBSA-based screening, and MD simulation study |
Essential Oils | 📋 | | ⛔ | | 38136228 | Essential Oils in Cervical Cancer: Narrative Review on Current Insights and Future Prospects |
Ferulic Acid | 📋 | ✍ | ⛔ | | 37446770 | Quercetin and Ferulic Acid Elicit Estrogenic Activities In Vivo and In Silico |
Flaxseed Oil | 📋 | ✍ | ⛔ | | 38469148 | Effects of flaxseed oil supplementation on metaphase II oocyte rates in IVF cycles with decreased ovarian reserve: a randomized controlled trial |
L-Citrulline | 📋 | ✍ | ⛔ | | 37466772 | Pathophysiology of Preeclampsia and L-Arginine/L-Citrulline Supplementation as a Potential Strategy to Improve Birth Outcomes |
Lavender Essential Oil | 📋 | ✍ | ⛔ | | 37495431 | Effect of a lavender essential oil and sleep hygiene protocol on insomnia in postmenopausal women: A pilot randomized clinical trial |
Mangiferin | 📋 | | ⛔ | | 33822512 | Mangiferin Inhibits Inflammation and Cell Proliferation, and Activates Proapoptotic Events via NF-κB Inhibition in DMBA-Induced Mammary Carcinogenesis in Rats |
Mangosteen | 📋 | ✍ | ⛔ | | 36248245 | A Review of Herbal Medicine-Based Phytochemical of Garcinia as Molecular Therapy for Breast Cancer |
Peony | 📋 | | ⛔ | | 38139073 | Peony Pollen Protects against Primary Dysmenorrhea in Mice by Inhibiting Inflammatory Response and Regulating the COX2/PGE2 Pathway |
Pine Bark | 📋 | ✍ | ⛔ | | 32064827 | Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox® |
Polydatin | 📋 | ✍ | | | 38323270 | Polydatin ameliorates low-density lipoprotein cholesterol and lipid metabolism by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9) in triple-negative breast cancer with hyperlipidemia |
PUFA | 📋 | | | | 35053184 | Insight on Polyunsaturated Fatty Acids in Endometrial Receptivity |
Rapamycin | 📋 | ✍ | | | 37787375 | A systems biology approach and in vitro experiment indicated Rapamycin targets key cancer and cell cycle-related genes and miRNAs in triple-negative breast cancer cells |
Rosemary | 📋 | ✍ | ⛔ | | 32012648 | Rosemary Extract Inhibits Proliferation, Survival, Akt, and mTOR Signaling in Triple-Negative Breast Cancer Cells |
Sea Buckthorn | 📋 | ✍ | ⛔ | | 38027169 | Sea buckthorn, its bioactive constituents, and mechanism of action: potential application in female reproduction |
Spirulina | 📋 | ✍ | ⛔ | | 35691155 | Spirulina phycocyanin extract and its active components suppress epithelial-mesenchymal transition process in endometrial cancer via targeting TGF-beta1/SMAD4 signaling pathway |
Tongkat Ali | 📋 | ✍ | ⛔ | | 36013514 | Eurycoma longifolia (Jack) Improves Serum Total Testosterone in Men: A Systematic Review and Meta-Analysis of Clinical Trials |
TUDCA | 📋 | ✍ | ⛔ | | 35883766 | The Effect of Tauroursodeoxycholic Acid (TUDCA) Treatment on Pregnancy Outcomes and Vascular Function in a Rat Model of Advanced Maternal Age |
Antioxidants | 📋 | | ⛔ | | 38251706 | Efficacy of antioxidant supplementation in improving endocrine, hormonal, inflammatory, and metabolic statuses of PCOS: a meta-analysis and systematic review |
Barberry | 📋 | ✍ | ⛔ | | 35579124 | Berberis aristata DC Extract Counteracts the High Fat Diet Induced Reproductive Toxicity in Female Wistar Rats via Modulating Oxidative Stress and Resistance to Leptin and Insulin |
Bromelain | 📋 | ✍ | ⛔ | | 31752555 | Bromelain Enhances the Anti-tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo |
Capsaicin | 📋 | ✍ | ⛔ | | 37543862 | Synergistic Effects of Capsaicin and Quercetin Improved Induced Premature Ovarian Failure in Rat |
Choline | 📋 | ✍ | ⛔ | | 38607338 | Choline in pregnant women: a systematic review and meta-analysis |
Cranberry | 📋 | ✍ | ⛔ | | 35052555 | Human Milk Antioxidative Modifications in Mastitis: Further Beneficial Effects of Cranberry Supplementation |
Diosmin | 📋 | ✍ | ⛔ | | 34582664 | The Growth Suppression Activity of Diosmin and PGV-1 Co-Treatment on 4T1 Breast Cancer Targets Mitotic Regulatory Proteins |
Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 38466005 | Eicosapentaenoic Acid Alleviates Inflammatory Response and Insulin Resistance in Pregnant Mice With Gestational Diabetes Mellitus |
Glabridin | 📋 | | | | 37984749 | Natural isoflavone glabridin targets PI3Kγ as an adjuvant to increase the sensitivity of MDA-MB-231 to tamoxifen and DU145 to paclitaxel |
Guava | 📋 | | ⛔ | | 36358576 | Guava Leaf Essential Oil as a Potent Antioxidant and Anticancer Agent: Validated through Experimental and Computational Study |
Lemon Balm | 📋 | ✍ | ⛔ | | 33465795 | The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial |
Marigold | 📋 | ✍ | ⛔ | | 37371972 | Different Extraction Procedures Revealed the Anti-Proliferation Activity from Vegetable Semi-Purified Sources on Breast Cancer Cell Lines |
NAD | 📋 | | | | 38698835 | Supplementation with NAD+ and its precursors: A rescue of female reproductive diseases |
Paeoniflorin | 📋 | | | | 38138611 | Paeoniflorin Alleviates Cisplatin-Induced Diminished Ovarian Reserve by Restoring the Function of Ovarian Granulosa Cells via Activating FSHR/cAMP/PKA/CREB Signaling Pathway |
Pomegranate Seed extract | 📋 | | ⛔ | | 36034084 | Pomegranate seed extract enhances the inhibitory effect of adipose-derived mesenchymal stem cells on breast cancer cell line in co-culture conditions |
Prebiotics | 📋 | ✍ | ⛔ | | 38463778 | Vaginal microbiota: Potential targets for vulvovaginal candidiasis infection |
SAMe | 📋 | ✍ | ⛔ | | 36612044 | Co-Targeting Luminal B Breast Cancer with S-Adenosylmethionine and Immune Checkpoint Inhibitor Reduces Primary Tumor Growth and Progression, and Metastasis to Lungs and Bone |
St. Johns Wort | 📋 | ✍ | ⛔ | | 38599178 | Ganoderma lucidum and Hypericum perforatum exhibit anti-inflammatory, antioxidant and anti-androgen effect in rat model of experimental polycystic ovarian syndrome |
Thyme | 📋 | ✍ | ⛔ | | 37663807 | Cytotoxicity screening of Thymus vulgaris L. in breast cancer: in vitro study |
Asiatic Acid | 📋 | | | | 36672499 | Synergistic Combination of Luteolin and Asiatic Acid on Cervical Cancer In Vitro and In Vivo |
Beets | 📋 | ✍ | ⛔ | | 37313053 | Effect of Beta vulgaris extracts on dysmenorrhea among adolescent girls |
Berries | 📋 | | | | 22300613 | Influence of berry polyphenols on receptor signaling and cell-death pathways: implications for breast cancer prevention |
Caffeine | 📋 | ✍ | ⛔ | | 37833894 | Synergistic Effect of Saccharin and Caffeine on Antiproliferative Activity in Human Ovarian Carcinoma Ovcar-3 Cells |
Calycosin | 📋 | | | | 37393829 | Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway |
Cat's Claw | 📋 | ✍ | ⛔ | | 34773881 | Uncaria tomentosa extract (AC-11) improves pregnancy hypertension together with suppression of sFlt-1 and sEng |
Chaga Mushrooms | 📋 | ✍ | ⛔ | | 38268969 | Synergistic Cytotoxicity of Extracts of Chaga Mushroom and Microalgae against Mammalian Cancer Cells In Vitro |
Chlorella | 📋 | ✍ | ⛔ | | 37387377 | Synergism of antiproliferative effects of young green barley and chlorella water extracts against human breast cancer cells |
Coconut Oil | 📋 | | ⛔ | | 38106629 | Assessment of the neuroprotective effect of Cocos nucifera L. oil on learning and behavior impairment in ovariectomized rats |
Cordycepin | 📋 | | | | 38720766 | Cordycepin enhances anti-tumor immunity in breast cancer by enhanceing ALB expression |
Echinacoside | 📋 | | | | 37865269 | Echinacoside regulates PI3K/AKT/HIF-1α/VEGF cross signaling axis in proliferation and apoptosis of breast cancer |
Fiber | 📋 | ✍ | ⛔ | | 37791847 | Diet-Related Risk Factors for Cervical Cancer: Data from National Health and Nutrition Examination Survey 1999-2018 |
Fruits | 📋 | | | | 38102975 | Modifiable prognostic factors in uterine fibroid development: a systematic review of literature |
Galangal | 📋 | ✍ | ⛔ | | 35204176 | 1'-Acetoxyeugenol Acetate Isolated from Thai Ginger Induces Apoptosis in Human Ovarian Cancer Cells by ROS Production via NADPH Oxidase |
Galangin | 📋 | | | | 32235536 | Galangin, a Flavonoid from Lesser Galangal, Induced Apoptosis via p53-Dependent Pathway in Ovarian Cancer Cells |
Geranium Essential Oil | 📋 | | ⛔ | | 30914034 | Foeniculum Vulgare and Pelargonium Graveolens Essential Oil Mixture Triggers the Cell Cycle Arrest and Apoptosis in MCF-7 Cells |
Icaritin | 📋 | | | | 37689142 | Icaritin attenuates recurrent spontaneous abortion in mice by modulating Treg/Th17 imbalance via TGF-β/SMAD signaling pathway |
Indian Gooseberry | 📋 | | ⛔ | | 37576627 | Hypophyllanthin and Phyllanthin from Phyllanthus niruri Synergize Doxorubicin Anticancer Properties against Resistant Breast Cancer Cells |
Inulin | 📋 | ✍ | ⛔ | | 37240357 | Dietary Supplementation of Inulin Contributes to the Prevention of Estrogen Receptor-Negative Mammary Cancer by Alteration of Gut Microbial Communities and Epigenetic Regulations |
Maca Root | 📋 | ✍ | ⛔ | | 36593713 | Efficacy and Safety of Maca ( Lepidium meyenii) in Patients with Symptoms of Late-Onset Hypogonadism: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial |
Morusin | 📋 | | | | 38522564 | Morusin inhibits breast cancer-induced osteolysis by decreasing phosphatidylinositol 3-kinase (PI3K)-mTOR signalling |
Nicotinamide | 📋 | ✍ | ⛔ | | 36648023 | Nicotinamide Riboside Preserves Ovarian Injury in Experimental Sepsis Model in Rats |
Pistachio | 📋 | ✍ | ⛔ | | 38707920 | A diet enriched with Pistacia atlantica fruits improves the female rats' reproductive system |
Prunella Vulgaris | 📋 | ✍ | ⛔ | | 38484956 | Effect and mechanism of Prunella vulgaris L. extract on alleviating lipopolysaccharide-induced acute mastitis in protecting the blood-milk barrier and reducing inflammation |
Salvianolic Acid | 📋 | | | | 38611749 | The Effect of Salvianolic Acid A on Tumor-Associated Macrophage Polarization and Its Mechanisms in the Tumor Microenvironment of Triple-Negative Breast Cancer |
Scutellarin | 📋 | | | | 38518647 | Scutellarin, a flavonoid compound from Scutellaria barbata, suppresses growth of breast cancer stem cells in vitro and in tumor-bearing mice |
Shiitake Mushrooms | 📋 | ✍ | ⛔ | | 38417905 | The Tumor Growth Inhibitory Effect of a Standardized Extract of Cultured Lentinula edodes Mycelia Using Patient Derived Xenograft Model |
Shogaol | 📋 | | | | 36937441 | The inhibitory effect of 6-gingerol and cisplatin on ovarian cancer and antitumor activity: In silico, in vitro, and in vivo |
Silymarin | 📋 | ✍ | ⛔ | | 38227082 | Co-treatment of silymarin and cisplatin inhibited cell proliferation, induced apoptosis in ovarian cancer |
Strawberry | 📋 | ✍ | ⛔ | | 31621765 | Isolation of Strawberry Anthocyanin-Rich Fractions and Their Mechanisms of Action Against Murine Breast Cancer Cell Lines |
Thymol | 📋 | ✍ | ⛔ | | 38376297 | Induction of G0/G1 phase cell cycle arrest and apoptosis by thymol through ROS generation and caspase-9/-3 activation in breast and colorectal cancer cell lines |
Almond | 📋 | | ⛔ | | 34856918 | Investigation of the effect of Prunus Amygdalus Amara on the expression of some genes of apoptosis and immortality in breast cancer cells (MCF-7) |
Andrographis | 📋 | ✍ | ⛔ | | 38248336 | Cytotoxic Effect of Andrographis paniculata Associated with 2-Aminoethyl Dihydrogen Phosphate in Triple-Negative Breast Cells |
Carnosol | 📋 | | | | 37507889 | Targeting Triple-Negative Breast Cancer by the Phytopolyphenol Carnosol: ROS-Dependent Mechanisms |
Date | 📋 | | ⛔ | | 35291987 | Anticancer potential of Phoenix dactylifera L. seed extract in human cancer cells and pro-apoptotic effects mediated through caspase-3 dependent pathway in human breast cancer MDA-MB-231 cells: an in vitro and in silico investigation |
Diosgenin | 📋 | | | | 38538058 | Diosgenin inhibits proliferation and migration of ovarian cancer cells and induce apoptosis via upregulation of PTEN |
Equol | 📋 | ✍ | ⛔ | | 35128842 | Evaluation of a natural S-equol supplement in treating premenstrual symptoms and the effect of the gut microbiota: An open-label pilot study |
Escin | 📋 | ✍ | ⛔ | | 37149513 | Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin |
Frankincense Essential Oil | 📋 | | ⛔ | | 30119267 | Cytotoxicity and apoptosis enhancement in breast and cervical cancer cells upon coadministration of mitomycin C and essential oils in nanoemulsion formulations |
Glycyrrhetinic Acid | 📋 | | | | 37011418 | Glycyrrhetinic acid suppresses breast cancer metastasis by inhibiting M2-like macrophage polarization via activating JNK1/2 signaling |
Haritaki | 📋 | ✍ | ⛔ | | 37706181 | Cell cycle arrest and apoptotic studies of Terminalia chebula against MCF-7 breast cancer cell line: an in vitro and in silico approach |
Honey | 📋 | ✍ | ⛔ | | 38667044 | Medical-Grade Honey as a Potential New Therapy for Bacterial Vaginosis |
Hops | 📋 | ✍ | ⛔ | | 37101856 | Effect of Humulus lupulus L. (Hop) on Postmenopausal Sexual Dysfunction: A Randomized Clinical Trial |
Lactobacillus plantarum | 📋 | | ⛔ | | 38235890 | Efficacy and safety of Lactobacillus plantarum P 17630 strain soft vaginal capsule in vaginal candidiasis: a randomized non-inferiority clinical trial |
Liquiritigenin | 📋 | | | | 37253812 | Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women's breast tissue |
Magnolol | 📋 | | | | 38375055 | Magnolol and 5-fluorouracil synergy inhibition of metastasis of cervical cancer cells by targeting PI3K/AKT/mTOR and EMT pathways |
Marjoram | 📋 | | ⛔ | | 37887408 | Effects of Origanum majorana on Breast Cancer Cells: An Alternative to Chemotherapy? |
Morin | 📋 | | | | 37242455 | Morin Sensitizes MDA-MB-231 Triple-Negative Breast Cancer Cells to Doxorubicin Cytotoxicity by Suppressing FOXM1 and Attenuating EGFR/STAT3 Signaling Pathways |
Mulberry | 📋 | | ⛔ | | 35956414 | Beneficial Effects of Flaxseed and/or Mulberry Extracts Supplementation in Ovariectomized Wistar Rats |
Myrrh | 📋 | ✍ | ⛔ | | 35106067 | Experience with nutraceutical supplements in the treatment of pelvic pain in gynaecology: case reports |
Myrtle | 📋 | ✍ | ⛔ | | 32615837 | Efficacy of a vaginal tablet as a Persian medicine product on vulvovaginal candidiasis: a double-blind, randomised, placebo-controlled trial |
Neem | 📋 | ✍ | | | 36088372 | Methanolic neem (Azadirachta indica) stem bark extract induces cell cycle arrest, apoptosis and inhibits the migration of cervical cancer cells in vitro |
Nicotinamide Riboside | 📋 | ✍ | ⛔ | | 38684562 | Nicotinamide Mononucleotide and Nicotinamide Riboside Reverse Ovarian Aging in Rats Via Rebalancing Mitochondrial Fission and Fusion Mechanisms |
Olive Polyphenols | 📋 | | | | 37292535 | Olive: A Potential Suppressor for Cervical Cancer by Upregulation of P21 |
Ollive Leaf extract | 📋 | ✍ | ⛔ | | 33598284 | Treatment of genital herpes using olive leaf extract |
Onion | 📋 | ✍ | ⛔ | | 38263589 | Patterns of proliferation and fibrosis in a rat model of endometriosis following administration of Allium cepa |
Piperlongumine | 📋 | | | | 38279841 | Piperlongumine inhibits antioxidant enzymes, increases ROS levels, induces DNA damage and G2/M cell cycle arrest in breast cell lines |
PQQ | 📋 | ✍ | ⛔ | | 38581065 | Pyrroloquinoline quinone promotes human mesenchymal stem cell-derived mitochondria to improve premature ovarian insufficiency in mice through the SIRT1/ATM/p53 pathway |
Roselle | 📋 | ✍ | ⛔ | | 37314593 | The Phytoestrogenic Effect of Hibiscus sabdariffa Involves Estrogen Receptor α in Ovariectomized Wistar Rats |
Safflower | 📋 | ✍ | ⛔ | | 38063123 | Carthamus Tınctorius L. (Safflower) extracts inhibit expression of metastatic genes of MDA-MB-231 breast cancer cells |
Schisandra | 📋 | ✍ | ⛔ | | 34440602 | Gomisin L1, a Lignan Isolated from Schisandra Berries, Induces Apoptosis by Regulating NADPH Oxidase in Human Ovarian Cancer Cells |
Sesamol | 📋 | | | | 37274057 | Transcriptome Profiling Analysis of Breast Cancer Cell MCF-7 Treated by Sesamol |
Tetrahydrocurcumin | 📋 | ✍ | | | 36707875 | Tetrahydrocurcumin regulates the tumor immune microenvironment to inhibit breast cancer proliferation and metastasis via the CYP1A1/NF-κB signaling pathway |
Urolithins | 📋 | | | | 38615740 | Urolithin a inhibits breast cancer progression via activating TFEB-mediated mitophagy in tumor macrophages |
Vitamin B1 | 📋 | ✍ | ⛔ | | 38368515 | The Effects of Thiamine Supplementation on General Health and Infertility Treatment Outcomes in Women with Polycystic Ovary Syndrome: A Triple-Blinded Randomized Placebo-Controlled Clinical Trial |
Acacetin | 📋 | | | | 36740148 | Acacetin induces sustained ERK1/2 activation and RIP1-dependent necroptotic death in breast cancer cells |
Aged Garlic | 📋 | ✍ | ⛔ | | 37352173 | Aged black garlic extract inhibits the growth of estrogen receptor-positive breast cancer cells by downregulating MCL-1 expression through the ROS-JNK pathway |
Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 36797668 | Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition |
Anise | 📋 | ✍ | ⛔ | | 32692701 | Could Anise decrease the intensity of premenstrual syndrome symptoms in comparison to placebo? A double-blind randomized clinical trial |
Apple Polyphenols | 📋 | | ⛔ | | 32985606 | Annurca apple polyphenol extract promotes mesenchymal-to-epithelial transition and inhibits migration in triple-negative breast cancer cells through ROS/JNK signaling |
Asiaticoside | 📋 | | | | 36903346 | Asiaticoside Increases Caspase-9 Activity in MCF-7 Cells and Inhibits TNF-α and IL-6 Expression in Nude Mouse Xenografts via the NF-κB Pathway |
Asparagus | 📋 | | ⛔ | | 38685363 | Molecular Mechanisms of Asparagus racemosus Willd. and Withania somnifera (L.) Dunal as Chemotherapeutic Adjuvants for Breast Cancer Treatment |
Astragalin | 📋 | | | | 36195046 | Mixed computational-experimental study to reveal the anti-metastasis and anti-angiogenesis effects of Astragalin in human breast cancer |
Avocado | 📋 | ✍ | ⛔ | | 38661065 | Ethanolic extract of Persea americana Mill. (Lauraceae) seeds induced antiestrogenic effects in young female Wistar rats |
Beta-Cryptoxanthin | 📋 | | | | 31892217 | Chemopreventive Effect of β-Cryptoxanthin on Human Cervical Carcinoma (HeLa) Cells Is Modulated through Oxidative Stress-Induced Apoptosis |
Bilberry | 📋 | ✍ | ⛔ | | 34944868 | Anthocyanidins Inhibit Growth and Chemosensitize Triple-Negative Breast Cancer via the NF-κB Signaling Pathway |
Bitter Melon | 📋 | ✍ | ⛔ | | 38173546 | Exploring the mechanism of action bitter melon in the treatment of breast cancer by network pharmacology |
Black Pepper | 📋 | ✍ | ⛔ | | 37464192 | Piper nigrum extract suppresses tumor growth and enhances the antitumor immune response in murine models of breast cancer and melanoma |
Cherry | 📋 | | ⛔ | | 36364072 | Dark Sweet Cherry ( Prunus avium) Anthocyanins Suppressed ERK1/2-Akt/mTOR Cell Signaling and Oxidative Stress: Implications for TNBC Growth and Invasion |
Chokeberry | 📋 | ✍ | ⛔ | | 35739998 | Antioxidative Effects of Standardized Aronia melanocarpa Extract on Reproductive and Metabolic Disturbances in a Rat Model of Polycystic Ovary Syndrome |
Citral | 📋 | | | | 38545203 | Untargeted metabolomics uncovers prime pathways linked to antibacterial action of citral against bacterial vaginosis-causing Gardnerella vaginalis: An in vitro and in vivo study |
Cordyceps | 📋 | ✍ | ⛔ | | 33421460 | Cordyceps cicadae polysaccharides inhibit human cervical cancer hela cells proliferation via apoptosis and cell cycle arrest |
Delphinidin | 📋 | | | | 35713123 | Effect of Delphinidin on Metabolomic Profile in Breast Carcinogenesis |
Diallyl Disulfide | 📋 | | | | 35690339 | Insight into drug sensitizing effect of diallyl disulfide and diallyl trisulfide from Allium sativum L. on paclitaxel-resistant triple-negative breast cancer cells |
Dihydroartemisinin | 📋 | | | | 37490927 | Dihydroartemisinin inhibits angiogenesis in breast cancer via regulating VEGF and MMP-2/-9 |
DIM | 📋 | ✍ | ⛔ | | 36467932 | Diindolylmethane Promotes Metabolic Crisis and Enhances the Efficacy of Centchroman in Breast Cancer: A 1H NMR-Based Approach |
Dioscin | 📋 | | | | 36757991 | In vitro evaluation of dioscin and protodioscin against ER-positive and triple-negative breast cancer |
Eucalyptus | 📋 | ✍ | ⛔ | | 35967023 | Antiproliferative Activities of the Lipophilic Fraction of Eucalyptus camaldulensis against MCF-7 Breast Cancer Cells, UPLC-ESI-QTOF-MS Metabolite Profile, and Antioxidative Functions |
Gamma-Linolenic Acid | 📋 | ✍ | ⛔ | | 34472451 | A basal level of γ-linolenic acid depletes Ca 2+ stores and induces endoplasmic reticulum and oxidative stresses to cause death of breast cancer BT-474 cells |
Ginger Essential Oil | 📋 | ✍ | | | 33376534 | Isobaric tags for relative and absolute quantitation-based proteomics analysis of the effect of ginger oil on bisphenol A-induced breast cancer cell proliferation |
Hawthorn | 📋 | ✍ | ⛔ | | 35262883 | In Vitro Anti-cancer Effect of Crataegus oxyacantha Berry Extract on Hormone Receptor Positive and Triple Negative Breast Cancers via Regulation of Canonical Wnt Signaling Pathway |
Iodine | 📋 | ✍ | ⛔ | | 37836466 | Iodized Salt May Not Be Sufficient to Guarantee an Adequate Iodine Intake in Pregnant Women |
Isorhamnetin | 📋 | | | | 37004402 | Isorhamnetin induces cell cycle arrest and apoptosis by triggering DNA damage and regulating the AMPK/mTOR/p70S6K signaling pathway in doxorubicin-resistant breast cancer |
L-Lysine | 📋 | ✍ | ⛔ | | 38584530 | L-lysine Increases the Anticancer Effect of Doxorubicin in Breast Cancer by Inducing ROS-Dependent Autophagy |
Lotus | 📋 | | ⛔ | | 34820007 | Isoliensinine induces cervical cancer cell cycle arrest and apoptosis by inhibiting the AKT/GSK3α pathway |
Lupeol | 📋 | | | | 38047085 | Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer |
Modified Citrus Pectin | 📋 | ✍ | ⛔ | | 34462562 | Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment |
MSM | 📋 | ✍ | ⛔ | | 32562081 | Methylsulfonylmethane Sensitizes Endometrial Cancer Cells to Doxorubicin |
Neferine | 📋 | | | | 37303677 | Neferine mediated TGF-β/ERK signaling to inhibit fibrosis in endometriosis |
Oleanolic Acid | 📋 | | | | 38449659 | Oleanolic acid inhibits the tumor progression by regulating Lactobacillus through the cytokine-cytokine receptor interaction pathway in 4T1-induced mice breast cancer model |
Oolong Tea | 📋 | | ⛔ | | 33292347 | Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice |
Oregano Essential Oil | 📋 | ✍ | ⛔ | | 38067161 | Cytotoxic Effect Induced by Sicilian Oregano Essential Oil in Human Breast Cancer Cells |
Papaya | 📋 | ✍ | ⛔ | | 36988843 | Discovery of Potential Phytochemicals from Carica papaya Targeting BRCA-1 in Breast Cancer Treatment |
Parthenolide | 📋 | | | | 38141074 | Parthenolide inhibits the proliferation and migration of cervical cancer cells via FAK/GSK3β pathway |
PEA | 📋 | ✍ | ⛔ | | 38230286 | Exploring the Protective Effect against 7,12-Dimethylbenz[a]anthracene-Induced Breast Tumors of Palmitoylethanolamide |
Red Clover | 📋 | ✍ | ⛔ | | 33920485 | Evaluation of Clinical Meaningfulness of Red Clover ( Trifolium pratense L.) Extract to Relieve Hot Flushes and Menopausal Symptoms in Peri- and Post-Menopausal Women: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
Schisandrins | 📋 | | | | 38254674 | The Use of Schisandrin B to Combat Triple-Negative Breast Cancers by Inhibiting NLRP3-Induced Interleukin-1β Production |
Spikenard | 📋 | ✍ | ⛔ | | 32615837 | Efficacy of a vaginal tablet as a Persian medicine product on vulvovaginal candidiasis: a double-blind, randomised, placebo-controlled trial |
Stigmasterol | 📋 | | | | 36091246 | Phytosterol intake and overall survival in newly diagnosed ovarian cancer patients: An ambispective cohort study |
Syringic Acid | 📋 | | | | 38086229 | Syringic acid alleviates cisplatin-induced ovarian injury through modulating endoplasmic reticulum stress, inflammation and Nrf2 pathway |
Tea | 📋 | | | | 36678274 | Association between Different Types of Tea Consumption and Risk of Gynecologic Cancer: A Meta-Analysis of Cohort Studies |
Tea Tree Essential Oil | 📋 | | ⛔ | | 36763614 | Effect of Tea Tree Oil and Coconut Oil on Nipple Crack Formation in the Early Postpartum Period |
Telmisartan | 📋 | | ⛔ | | 37893423 | Robust Identification of Differential Gene Expression Patterns from Multiple Transcriptomics Datasets for Early Diagnosis, Prognosis, and Therapies for Breast Cancer |
Trans-Resveratrol | 📋 | | | | 36358483 | Markers of Endothelial Dysfunction Are Attenuated by Resveratrol in Preeclampsia |
Vegetables | 📋 | | | | 38479372 | The intake of cruciferous vegetables and the risk of ovarian cancer: a systematic review and dose-response meta-analysis |
Vitamin B2 | 📋 | ✍ | ⛔ | | 34836625 | Screening of the Prime bioactive compounds from Aloe vera as potential anti-proliferative agents targeting DNA |
Yam | 📋 | | | | 38211573 | Herbal treatment of female urogenital atrophy: A retrospective cohort analysis |
Basil | 📋 | ✍ | ⛔ | | 38024822 | Ethanol extract of basil ( Ocimum Basilicum L.) leaves inhibits endometriosis growth in a mouse model by modulating vascular endothelial growth factor (VEGF) expression |
BCAA | 📋 | ✍ | ⛔ | | 36847712 | BCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS |
Betulinic Acid | 📋 | | | | 38403724 | Betulinic acid induces apoptosis of HeLa cells via ROS-dependent ER stress and autophagy in vitro and in vivo |
Black Tea | 📋 | ✍ | ⛔ | | 30364631 | Synergistic effect of black tea polyphenol, theaflavin-3,3'-digallate with cisplatin against cisplatin resistant human ovarian cancer cells |
Caffeic Acid | 📋 | ✍ | ⛔ | | 35910085 | Caffeic Acid Phenethyl Ester as a DHODH Inhibitor and Its Synergistic Anticancer Properties in Combination with 5-Fluorouracil in a Breast Cancer Cell Line |
Cardamom | 📋 | ✍ | ⛔ | | 36522620 | Effect of green cardamom on the expression of genes implicated in obesity and diabetes among obese women with polycystic ovary syndrome: a double blind randomized controlled trial |
Cardamonin | 📋 | | | | 35860007 | Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition |
Carrot | 📋 | | ⛔ | | 33183662 | Evaluation of the effect of carrot seed (Daucus Carota) in women of fertile age with hypoactive sexual desire disorder: A randomized double-blind clinical trial |
Chamomile Essential Oil | 📋 | ✍ | ⛔ | | 36941224 | Chamomile Essential Oil: chemical constituents and antitumor activity in MDA-MB-231 cells through PI3K/Akt/mTOR signaling pathway |
Cheese | 📋 | | ⛔ | | 37969456 | Causal relationship association of cheese intake with gestational hypertension and diabetes result from a Mendelian randomization study |
Cinnamon Essential Oil | 📋 | ✍ | ⛔ | | 37375915 | Cinnamon Oil Alleviates Acetaminophen-Induced Uterine Toxicity in Rats by Abrogation of Oxidative Stress, Apoptosis, and Inflammation |
Clove | 📋 | | ⛔ | | 37183845 | The Effects of Clove Oil on The Biochemical and Histological Parameters, and Autophagy Markers in Polycystic Ovary Syndrome-Model Rats |
Copper | 📋 | ✍ | ⛔ | | 38139406 | Copper in Gynecological Diseases |
Coptis Chinensis | 📋 | | ⛔ | | 34457027 | Network Pharmacology-Based Strategy for Predicting Active Ingredients and Potential Targets of Coptis chinensis Franchin Polycystic Ovary Syndrome |
Cyanidin | 📋 | ✍ | | | 30782251 | Cyanidin-3- O-glucoside chloride acts synergistically with luteolin to inhibit the growth of colon and breast carcinoma cells |
Fish | 📋 | | ⛔ | | 35247886 | Association of fruit, vegetable and animal food intakes with breast cancer risk overall and by molecular subtype among Vietnamese women |
Fo-Ti Root | 📋 | ✍ | ⛔ | | 36111333 | 2,3,5,4'-Tetrahydroxystilbene-2- O-β-D-Glucoside improves female ovarian aging |
Geraniol | 📋 | | | | 37379815 | Geraniol suppresses tumour growth and enhances chemosensitivity of 5-fluorouracil on breast carcinoma in mice: involvement of miR-21/PTEN signalling |
Giloy | 📋 | ✍ | ⛔ | | 37901891 | Therapeutic Effect of Tinospora cordifolia (Willd) Extracts on Letrozole-Induced Polycystic Ovarian Syndrome and its Complications in Murine Model |
Ginkgetin | 📋 | | | | 37172479 | Ginkgetin suppresses ovarian cancer growth through inhibition of JAK2/STAT3 and MAPKs signaling pathways |
Ginkgolic Acid | 📋 | | | | 34987594 | Ginkgolic Acid (GA) Inhibits the Growth of OCa by Inhibiting lncRNA MALAT1/JAK2 Axis |
Hazelnut | 📋 | | ⛔ | | 28258038 | Viability-reducing activity of Coryllus avellana L. extracts against human cancer cell lines |
L-Tryptophan | 📋 | ✍ | ⛔ | | 33752438 | [L-tryptophan as dietetic supplement and treatment for hot flashes, astenia, and insomnia in cancer patients] |
Lavender | 📋 | ✍ | ⛔ | | 37931721 | Lavender and metformin effectively propagate progesterone levels in patients with polycystic ovary syndrome: A randomized, double-blind clinical trial |
Linalool | 📋 | | ⛔ | | 35976268 | Antifungal activity of linalool against fluconazole-resistant clinical strains of vulvovaginal Candida albicans and its predictive mechanism of action |
Linoleic Acid | 📋 | ✍ | ⛔ | | 38465855 | Linoleic acid exhibits anti-proliferative and anti-invasive activities in endometrial cancer cells and a transgenic model of endometrial cancer |
Liquiritin | 📋 | | | | 35733703 | Protective effects of liquiritin on polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis via miR-206/PI3K/AKT pathway |
Lychee | 📋 | | ⛔ | | 36603788 | Total flavonoids of Litchi seed attenuate stem cell-like properties in breast cancer by regulating Notch3 signaling pathway |
Mushrooms | 📋 | | ⛔ | | 37373268 | Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer |
Neroli Essential Oil | 📋 | ✍ | ⛔ | | 38148005 | Anti-inflammatory, antioxidant, antiangiogenic, and therapeutic efficacy of neroli oil in rats with endometriotic lesions |
Nimbolide | 📋 | | | | 35212444 | Protective effect of nimbolide against streptozotocin induced gestational diabetes mellitus in rats via alteration of inflammatory reaction, oxidative stress, and gut microbiota |
Noni | 📋 | | ⛔ | | 38662247 | Noni enhances the anticancer activity of cyclophosphamide and suppresses myelotoxicity and hepatotoxicity in tumor-bearing mice |
Nuciferine | 📋 | | | | 37734199 | Nuciferine protects against lipopolysaccharide-induced endometritis via inhibiting ferroptosis and modulating AMPKα/mTOR/HIF-1α signaling axis |
Oats | 📋 | | ⛔ | | 34337029 | Protective Effects of A. sativa against Oxidative Stress-Induced Liver Damage in Ovariectomized Mice |
Omega-6 Fatty Acids | 📋 | ✍ | ⛔ | | 34944997 | Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells |
Orange | 📋 | | ⛔ | | 20691333 | Dietary consumption of antioxidant nutrients and risk of incident cervical intraepithelial neoplasia |
Pau d'Arco | 📋 | ✍ | ⛔ | | 36960315 | Safety and tolerability of Pau d' Arco ( Tabebuia avellanedae) for primary dysmenorrhea: A single-arm, open-label trial on adults ages 18-45 |
Peach | 📋 | | ⛔ | | 24996346 | Polyphenols of selected peach and plum genotypes reduce cell viability and inhibit proliferation of breast cancer cells while not affecting normal cells |
Peanut | 📋 | | ⛔ | | 35163062 | Arachidin-1, a Prenylated Stilbenoid from Peanut, Induces Apoptosis in Triple-Negative Breast Cancer Cells |
Pectin | 📋 | ✍ | ⛔ | | 37898255 | Modified pectin with anticancer activity in breast cancer: A systematic review |
Phloretin | 📋 | | | | 38423666 | Phloretin Inhibits the Proliferation of Breast Cancer Cells Through the Down-regulation of Estrogen Receptor α |
Phosphatidylcholine | 📋 | ✍ | ⛔ | | 36354156 | Relationship between different forms of dietary choline and ovarian cancer survival: findings from the ovarian cancer follow-up study, a prospective cohort study |
Plum | 📋 | | ⛔ | | 24996346 | Polyphenols of selected peach and plum genotypes reduce cell viability and inhibit proliferation of breast cancer cells while not affecting normal cells |
Poria Mushrooms | 📋 | ✍ | | | 37831733 | Preclinical study of pachyman inducing ferroptosis against ovarian cancer: Biological targets and underlying mechanisms |
Pumpkin Seed | 📋 | ✍ | ⛔ | | 38397839 | Evaluation of Antioxidant Effects of Pumpkin ( Cucurbita pepo L.) Seed Extract on Aging- and Menopause-Related Diseases Using Saos-2 Cells and Ovariectomized Rats |
Sesame | 📋 | ✍ | ⛔ | | 38515384 | Dietary supplementation with seeds of Sesamum indicum L. (pedaliaceae) mitigates the 7,12-dimethylbenz(a)anthracene-induced breast tumor burden in rats |
Soy Protein | 📋 | ✍ | ⛔ | | 37890205 | Protective effect of soy isolate protein against streptozotocin induced gestational diabetes mellitus via TLR4/MyD88/NF-κB signaling pathway |
Soybean Oil | 📋 | | ⛔ | | 24250433 | Comparison of piascledine (avocado and soybean oil) and hormone replacement therapy in menopausal-induced hot flashing |
Spearmint | 📋 | | ⛔ | | 32197626 | A combination of spearmint and flaxseed extract improved endocrine and histomorphology of ovary in experimental PCOS |
Spices | 📋 | | | | 36103746 | Interactive bioinformatics analysis for the screening of hub genes and molecular docking of phytochemicals present in kitchen spices to inhibit CDK1 in cervical cancer |
St. Johns Wort Oil | 📋 | | ⛔ | | 36367811 | The efficacy of St John's wort oil macerates on intractable skin lesions of patients with idiopathic granulomatous mastitis: preliminary results |
Taurine | 📋 | ✍ | ⛔ | | 38630910 | Taurine Inhibits Lung Metastasis in Triple-Negative Breast Cancer by Modulating Macrophage Polarization Through PTEN-PI3K/Akt/mTOR Pathway |
Thyme Essential Oil | 📋 | | ⛔ | | 38144096 | Network Pharmacology Combined with Molecular Docking, Molecular Dynamics, and In Vitro Experimental Validation Reveals the Therapeutic Potential of Thymus vulgaris L. Essential Oil (Thyme Oil) against Human Breast Cancer |
Tomato | 📋 | | ⛔ | | 33901572 | α-Tomatine, a novel early-stage autophagy inhibitor, inhibits autophagy to enhance apoptosis via Beclin-1 in Skov3 cells |
Vitamin B3 | 📋 | ✍ | ⛔ | | 34748060 | Effect of maternal dietary niacin intake on congenital anomalies: a systematic review and meta-analysis |
Vitamin K2 | 📋 | ✍ | ⛔ | | 37030416 | Vitamin K2 enhances the tumor suppressive effects of 1,25(OH)2D3 in triple negative breast cancer cells |
Vitexin | 📋 | | | | 36994813 | Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway |
Whey Protein | 📋 | ✍ | ⛔ | | 34371959 | Whey Protein Supplementation Improves the Glycemic Response and May Reduce Non-Alcoholic Fatty Liver Disease Related Biomarkers in Women with Polycystic Ovary Syndrome (PCOS) |
White Mushrooms | 📋 | | ⛔ | | 37421350 | Protective effect of Agaricus bisporus mushroom against maternal and fetal damage induced by lead administration during pregnancy in rats |
White Tea | 📋 | | ⛔ | | 34369381 | Effect of white tea consumption on serum leptin, TNF-α and UCP1 gene expression in ovariectomized rats |
Yogurt | 📋 | | ⛔ | | 37062185 | Effect of probiotic yogurt on gestational diabetes mellitus: A systematic review and meta-analysis |
Zeaxanthin | 📋 | ✍ | ⛔ | | 26482064 | Specific Serum Carotenoids Are Inversely Associated With Breast Cancer Risk Among Chinese Women: A Case-Control Study |
Aloin | 📋 | | | | 33456413 | Barbaloin Treatment Contributes to the Rebalance of Glucose and Lipid Homeostasis of Gestational Diabetes Mellitus Mice |
Amino Acids | 📋 | | | | 34420200 | Effect of Vitamin-Containing Amino Acid Supplements on Menopausal Symptoms and Age-Related Skin Changes: A Randomised, Double-Blind, Placebo-Controlled Study |
Anethole | 📋 | | | | 36029056 | The Protective Effects of Trans-Anethole against Polycystic Ovary Syndrome Induced Histopathological and Metabolic Changes in Rat |
Apricot Kernels | 📋 | ✍ | ⛔ | | 36364419 | Targeting Proteolysis with Cyanogenic Glycoside Amygdalin Induces Apoptosis in Breast Cancer Cells |
Arachidonic Acid | 📋 | ✍ | ⛔ | | 35946033 | Antibiofilm Activity of Essential Fatty Acids Against Candida albicans from Vulvovaginal Candidiasis and Bloodstream Infections |
Artemisinin | 📋 | | | | 38144525 | CLEC12A sensitizes differentially responsive breast cancer cells to the anti-cancer effects of artemisinin by repressing autophagy and inflammation |
Atractylodes | 📋 | ✍ | ⛔ | | 38358034 | Atractylodes macrocephala III suppresses EMT in cervical cancer by regulating IGF2BP3 through ETV5 |
Barley | 📋 | ✍ | ⛔ | | 37387377 | Synergism of antiproliferative effects of young green barley and chlorella water extracts against human breast cancer cells |
Beer | 📋 | | | | 37402233 | Effect of moderate beer consumption (with and without ethanol) on cardiovascular health in postmenopausal women |
Bergamot | 📋 | ✍ | ⛔ | | 33470446 | Essential oil, juice, and ethanol extract from bergamot confer improving effects against primary dysmenorrhea in rats |
Beta-Lapachone | 📋 | | | | 38518601 | Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells |
Black Ginger | 📋 | ✍ | ⛔ | | 37345122 | Cytotoxic Activity, Anti-Migration and In Silico Study of Black Ginger ( Kaempferia parviflora) Extract against Breast Cancer Cell |
Burdock | 📋 | | ⛔ | | 32509375 | Proapoptotic and Antiangiogenic Activities of Arctium Lappa L. on Breast Cancer Cell Lines |
Capsanthin | 📋 | | | | 33934088 | Capsanthin induces G1/S phase arrest, erlotinib-sensitivity and inhibits tumor progression by suppressing EZH2-mediated epigenetically silencing of p21 in triple-negative breast cancer cells |
Catalpol | 📋 | | | | 36067808 | Catalpol induces apoptosis in breast cancer in vitro and in vivo: Involvement of mitochondria apoptosis pathway and post-translational modifications |
Celery | 📋 | | ⛔ | | 34062080 | The effect of Apium graveolens L., Levisticum officinale and Calendula officinalis L. on cell viability, membrane integrity, steroidogenesis, and intercellular communication in mice Leydig cells in vitro |
Chicory | 📋 | ✍ | ⛔ | | 36219736 | Effects of Chicory and Fumitory on Hot Flashes Among Breast Cancer Survivors: A Randomized, Double-Blind Placebo-Controlled Trial |
Chitosan | 📋 | ✍ | ⛔ | | 38279177 | Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis |
Chrysanthemum | 📋 | ✍ | ⛔ | | 34858550 | Lomens-P0 (mixed extracts of Hordeum vulgare and Chrysanthemum zawadskii) regulate the expression of factors affecting premenstrual syndrome symptoms |
Citrus Fruits | 📋 | | ⛔ | | 37761178 | Citrus Carotenoid Extracts Exert Anticancer Effects through Anti-Proliferation, Oxidative Stress, and Mitochondrial-Dependent Apoptosis in MCF-7 Cells |
Clary Sage Essential Oil | 📋 | ✍ | ⛔ | | 22435409 | Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial |
Coconut | 📋 | | ⛔ | | 28529739 | Long-term supplementation with young coconut juice does not prevent bone loss but rather alleviates body weight gain in ovariectomized rats |
Cornus | 📋 | | | | 36696645 | The effect of Cornus mas fruit extract on vasomotor symptoms and sex hormones in postmenopausal women: a randomized, double-blind, clinical trial |
Costus | 📋 | ✍ | ⛔ | | 37858751 | Modulation of mammary tumour progression using murine model by ethanol root extract of Saussurea costus (falc.) lipsch |
Deodar Cedar | 📋 | | | | 36690306 | Cedrus deodara (Roxb. ex D.Don) G.Don bark fraction ameliorates metabolic, endocrine and ovarian dynamics in rats experiencing polycystic ovarian syndrome |
Dill | 📋 | | ⛔ | | 33997002 | Antioxidant and Anticancer Efficacies of Anethum graveolens against Human Breast Carcinoma Cells through Oxidative Stress and Caspase Dependency |
Diosmetin | 📋 | | | | 37652155 | Diosmetin alleviates S. aureus-induced mastitis by inhibiting SIRT1/GPX4 mediated ferroptosis |
Elderberry | 📋 | ✍ | ⛔ | | 33845752 | Effects of Sambucus Ebulus Extract on Cell Proliferation and Viability of Triple-Negative Breast Cancer: An In Vitro and In Vivo Study |
Fennel Essential Oil | 📋 | ✍ | ⛔ | | 35642658 | Essential oil of Foeniculum vulgare subsp. piperitum fruits exerts an anti‑tumor effect in triple‑negative breast cancer cells |
Ganoderic Acid | 📋 | | | | 38678954 | Ganoderic acid D attenuates gemcitabine resistance of triple-negative breast cancer cells by inhibiting glycolysis via HIF-1α destabilization |
Ginkgolides | 📋 | | | | 22505596 | Ginkgo May Sensitize Ovarian Cancer Cells to Cisplatin: Antiproliferative and Apoptosis-Inducing Effects of Ginkgolide B on Ovarian Cancer Cells |
Gotu Kola | 📋 | ✍ | ⛔ | | 36950702 | Experience With a Non-Hormonal Centella Asiatica, Hyaluronic Acid and Prebiotic-Based Vaginal Gel in Women With Recurrent Vulvovaginal Candidiasis: Case Studies |
HMB | 📋 | ✍ | ⛔ | | 33802646 | β-Hydroxy-β-Methylbutyrate (HMB) Supplementation Prevents Bone Loss during Pregnancy-Novel Evidence from a Spiny Mouse ( Acomys cahirinus) Model |
Holy Basil | 📋 | ✍ | ⛔ | | 27563220 | Purified Essential Oil From Ocimum Sanctum Linn. Triggers the Apoptotic Mechanism in Human Breast Cancer Cells |
Horny Goat Weed | 📋 | ✍ | ⛔ | | 32092821 | Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo |
Hyperoside | 📋 | | | | 37984122 | Hypericum perforatum L. protects against renal function decline in ovariectomy rat model by regulating expressions of NOS3 and AKT1 in AGE-RAGE pathway |
Irisin | 📋 | | | | 38643847 | Irisin as an emerging target in the regulation of reproductive functions in health and disease |
L-Glutamine | 📋 | ✍ | ⛔ | | 33426346 | Oral L-glutamine rescues fructose-induced poor fetal outcome by preventing placental triglyceride and uric acid accumulation in Wistar rats |
L-Methionine | 📋 | ✍ | ⛔ | | 33457340 | The Effects of Zinc Methionine on Reproductive and Thyroid Hormones in Rats with Polycystic Ovarian Syndrome |
L-Proline | 📋 | ✍ | ⛔ | | 26622412 | Effect of a Nutrient Mixture on the Localization of Extracellular Matrix Proteins in HeLa Human Cervical Cancer Xenografts in Female Nude Mice |
Lemon | 📋 | | ⛔ | | 36615313 | Ameliorative Effect of Citrus Lemon Peel Extract and Resveratrol on Premature Ovarian Failure Rat Model: Role of iNOS/Caspase-3 Pathway |
Lemongrass | 📋 | ✍ | ⛔ | | 34282694 | In Vitro Evaluation of Antioxidant and Anticancer Activity of Lemongrass ( Cymbopogon citratus (D.C.) Stapf) |
Ligustilide | 📋 | | | | 37698739 | Ligustilide enhances pregnancy outcomes via improvement of endometrial receptivity and promotion of endometrial angiogenesis in rats |
Mango | 📋 | | ⛔ | | 37169856 | Anticancer role of mango (Mangifera indica L.) peel and seed kernel extracts against 7,12- dimethylbenz[a]anthracene-induced mammary carcinogenesis in female rats |
Mango Leaf | 📋 | | ⛔ | | 34548817 | Mangifera indica (Mango): A Promising Medicinal Plant for Breast Cancer Therapy and Understanding Its Potential Mechanisms of Action |
Milk Thistle | 📋 | ✍ | ⛔ | | 34275811 | In-vitro evaluation of antiproliferative potential of various fractions of Silybum marianum using HeLa and HepG2 cell lines |
Myrrh Essential Oil | 📋 | | ⛔ | | 26666387 | β-Bisabolene, a Sesquiterpene from the Essential Oil Extract of Opoponax (Commiphora guidottii), Exhibits Cytotoxicity in Breast Cancer Cell Lines |
Nutmeg | 📋 | ✍ | ⛔ | | 33271245 | Methoxyeugenol regulates the p53/p21 pathway and suppresses human endometrial cancer cell proliferation |
Okra | 📋 | | ⛔ | | 35765486 | Anti-cancer activity of an ethanolic extract of red okra pods ( Abelmoschus esculentus L. Moench) in rats induced by N-methyl -N-nitrosourea |
Omega-9 Fatty Acids | 📋 | | | | 30216095 | Differential Potentiation of Retinoic Acid Effects against Human Breast Cancer Cells by Unsaturated Fatty Acids |
Oyster | 📋 | | ⛔ | | 36097247 | Effects of Aerobic Exercise Combined with Oyster Peptide Supplement on the Formation of CTX-induced Late-Onset Hypogonadism in Male Rats |
Patchouli | 📋 | ✍ | ⛔ | | 26042464 | Induction of Apoptosis in Endometrial Cancer (Ishikawa) Cells by Pogostemon cablin Aqueous Extract (PCAE) |
Perilla | 📋 | ✍ | | | 33628300 | Extracts of Perilla frutescens var. Acuta (Odash.) Kudo Leaves Have Antitumor Effects on Breast Cancer Cells by Suppressing YAP Activity |
Potassium | 📋 | ✍ | ⛔ | | 33391407 | Lower dietary mineral intake is significantly associated with cervical cancer risk in a population-based cross-sectional study |
Pu-erh Tea | 📋 | ✍ | ⛔ | | 28428754 | Pu-erh Tea Water Extract Mediates Cell Cycle Arrest and Apoptosis in MDA-MB-231 Human Breast Cancer Cells |
Pueraria Mirifica | 📋 | ✍ | ⛔ | | 35550707 | Effects of Pueraria mirifica on vaginal artery vascularization in postmenopausal women with genitourinary syndrome of menopause |
Pumpkin Seed Oil | 📋 | ✍ | ⛔ | | 21545273 | Improvement in HDL cholesterol in postmenopausal women supplemented with pumpkin seed oil: pilot study |
Rice | 📋 | | ⛔ | | 37854873 | Benefit of Asian pigmented rice bioactive compound and its implication in breast cancer: a systematic review |
Rose | 📋 | | | | 35605922 | Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome in Wistar rats |
Rose Essential Oil | 📋 | | | | 38074845 | Antifungal Activity of Bulgarian Rose Damascena Oil against Vaginitis-Causing Opportunistic Fungi |
Rosehip | 📋 | ✍ | ⛔ | | 32064827 | Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox® |
Safranal | 📋 | | | | 36173113 | Quantitative Phosphoproteomics and Acetylomics of Safranal Anticancer Effects in Triple-Negative Breast Cancer Cells |
Senolytics | 📋 | | | | 36555154 | Senolytic Therapy: A Potential Approach for the Elimination of Oncogene-Induced Senescent HPV-Positive Cells |
Sesamin | 📋 | ✍ | | | 35223101 | Pharmacological Properties to Pharmacological Insight of Sesamin in Breast Cancer Treatment: A Literature-Based Review Study |
Shilajit | 📋 | ✍ | ⛔ | | 34466597 | Mummy Induces Apoptosis Through Inhibiting of Epithelial-Mesenchymal Transition (EMT) in Human Breast Cancer Cells |
Spearmint Essential Oil | 📋 | ✍ | ⛔ | | 29399556 | Role of Essential Oil of Mentha Spicata (Spearmint) in Addressing Reverse Hormonal and Folliculogenesis Disturbances in a Polycystic Ovarian Syndrome in a Rat Model |
Spermidine | 📋 | | | | 37741320 | Spermidine suppresses oxidative stress and ferroptosis by Nrf2/HO-1/GPX4 and Akt/FHC/ACSL4 pathway to alleviate ovarian damage |
Star Anise | 📋 | ✍ | ⛔ | | 38196489 | Illicium verum anticancer activity against MDA-MB-231 cell line |
Stevia | 📋 | ✍ | ⛔ | | 35444350 | Histomorphological Changes in a Rat Model of Polycystic Ovary Syndrome and the Contribution of Stevia Leaf Extract in Modulating the Ovarian Fibrosis, VEGF, and TGF-β Immunoexpressions: Comparison with Metformin |
Tamarind | 📋 | | ⛔ | | 37987952 | Adverse effect of Tamarindus indica and tamoxifen combination on redox balance and genotoxicity of breast cancer cell |
Tannic Acid | 📋 | ✍ | ⛔ | | 37378933 | Induction of Unfolded Protein Response by Tannic Acid Triggers Apoptosis in MDA-MB-231 Breast Cancer Cells |
Tea Polyphenols | 📋 | | | | 35743146 | Antioxidative, Anti-Inflammatory, Anti-Obesogenic, and Antidiabetic Properties of Tea Polyphenols-The Positive Impact of Regular Tea Consumption as an Element of Prophylaxis and Pharmacotherapy Support in Endometrial Cancer |
Trehalose | 📋 | | ⛔ | | 35748379 | Trehalose decreases mRNA and protein expressions of c-Jun and JunB in human cervical cancer HeLa cells |
Vitamin K2 mk-4 | 📋 | ✍ | | | 26082424 | Real-time Cell Analysis of the Inhibitory Effect of Vitamin K2 on Adhesion and Proliferation of Breast Cancer Cells |
Vitamin K2 mk-7 | 📋 | ✍ | | | 35883082 | Effect of vitamin K2 administration on depression status in patients with polycystic ovary syndrome: a randomized clinical trial |
Wine | 📋 | | ⛔ | | 35230367 | Very-light alcohol consumption suppresses breast tumor progression in a mouse model |
Withanolides | 📋 | | | | 32947878 | Withanolide C Inhibits Proliferation of Breast Cancer Cells via Oxidative Stress-Mediated Apoptosis and DNA Damage |
5-HTP | 📋 | ✍ | ⛔ | | 16164376 | The potential of 5-hydryoxytryptophan for hot flash reduction: a hypothesis |
Almond Oil | 📋 | | ⛔ | | 32419817 | Comparing the Effect of Foot Massage with Grape Seed Oil and Sweet Almond Oil on Physiological Leg Edema in Primigravidae: A Randomized Clinical Trial |
Aloesin | 📋 | | | | 28702312 | Aloesin Suppresses Cell Growth and Metastasis in Ovarian Cancer SKOV3 Cells Through the Inhibition of the MAPK Signaling Pathway |
Amaranth | 📋 | | ⛔ | | 26396347 | Effect of supplementation of drumstick (Moringa oleifera) and amaranth (Amaranthus tricolor) leaves powder on antioxidant profile and oxidative status among postmenopausal women |
Anthocyanidins | 📋 | | | | 34944868 | Anthocyanidins Inhibit Growth and Chemosensitize Triple-Negative Breast Cancer via the NF-κB Signaling Pathway |
Apple Vinegar | 📋 | ✍ | ⛔ | | 29112940 | Vaginal Candidiasis Infection Treated Using Apple Cider Vinegar: A Case Report |
Arctiin | 📋 | | | | 35214097 | Arctiin Inhibits Cervical Cancer Cell Migration and Invasion through Suppression of S100A4 Expression via PI3K/Akt Pathway |
Argan Oil | 📋 | ✍ | ⛔ | | 26327867 | Skin hydration in postmenopausal women: argan oil benefit with oral and/or topical use |
Arnica | 📋 | ✍ | ⛔ | | 35790192 | Computational and In Vitro Approaches to Elucidate the Anti-cancer Effects of Arnica montana in Hormone-Dependent Breast Cancer |
Artichoke | 📋 | ✍ | ⛔ | | 35559863 | Hop and artichoke extracts inhibit expression of extracellular matrix components in uterine leiomyoma cells |
Bacopa Monnieri | 📋 | ✍ | ⛔ | | 38622289 | Exploring the immunomodulatory potential of Brahmi (Bacopa monnieri) in the treatment of invasive ductal carcinoma |
Banana | 📋 | | ⛔ | | 35311172 | Antioxidant activity of banana flesh and antiproliferative effect on breast and pancreatic cancer cells |
Bee Pollen | 📋 | ✍ | ⛔ | | 33555077 | Synergic effect of bee pollen and metformin on proliferation and apoptosis of granulosa cells: Rat model of polycystic ovary syndrome |
Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 33470446 | Essential oil, juice, and ethanol extract from bergamot confer improving effects against primary dysmenorrhea in rats |
Beta-Alanine | 📋 | ✍ | ⛔ | | 32432779 | Women Dealing With Hot Flushes: The Role of β-Alanine |
Bitter Orange | 📋 | ✍ | ⛔ | | 38328013 | The Effect of Citrus Aurantium Vaginal Cream on Vaginal Atrophy in Postmenopausal Women: A Quasi-experimental Study |
Black Tea Polyphenols | 📋 | | | | 15341993 | Black tea polyphenol theaflavins inhibit aromatase activity and attenuate tamoxifen resistance in HER2/neu-transfected human breast cancer cells through tyrosine kinase suppression |
Blackcurrant | 📋 | ✍ | ⛔ | | 37893207 | Blackcurrant Anthocyanins Improve Blood Lipids and Biomarkers of Inflammation and Oxidative Stress in Healthy Women in Menopause Transition without Changing Body Composition |
Boron | 📋 | ✍ | ⛔ | | 25906949 | Effects of Boron Supplementation on the Severity and Duration of Pain in Primary Dysmenorrhea |
Brazil Nut | 📋 | | ⛔ | | 36634075 | Antitumor effect of selenium-rich Brazil nuts and selenomethionine dietary supplementation on pre-existing 4T1 mammary tumor growth in mice |
Broccoli | 📋 | | ⛔ | | 35475592 | A Presurgical-Window Intervention Trial of Isothiocyanate-Rich Broccoli Sprout Extract in Patients with Breast Cancer |
Buckwheat | 📋 | | ⛔ | | 34890369 | Tartary buckwheat flavonoids relieve the tendency of mammary fibrosis induced by HFD during pregnancy and lactation |
Cabbage | 📋 | | ⛔ | | 36726900 | Red Cabbage: A Novel Treatment for Periductal Lactational Mastitis |
Camellia | 📋 | | ⛔ | | 33802884 | Theasaponin E 1 Inhibits Platinum-Resistant Ovarian Cancer Cells through Activating Apoptosis and Suppressing Angiogenesis |
Camphor | 📋 | ✍ | ⛔ | | 38410133 | Efficacy of a vaginal suppository formulation prepared with Acacia arabica (Lam.) Willd. gum and Cinnamomum camphora (L.) J. Presl. in heavy menstrual bleeding analyzed using a machine learning technique |
Cantaloupe | 📋 | | ⛔ | | 36381669 | Evaluation of morphology and angiogenesis of breast cancer in BALB/c mice using trypsin inhibitor from Cucumis melo seeds. In vitro and in vivo study |
Castor Oil | 📋 | ✍ | ⛔ | | 33565349 | Ricinus communis Butanol Fraction Inhibits MCF-7 Breast Cancer Cell Migration, Adhesion, and Invasiveness |
Chia Seeds | 📋 | | ⛔ | | 37437332 | Protective effect of Salvia hispanica (chia seeds) against obesity induced ovarian disorders in rat model |
Chicoric Acid | 📋 | | | | 36403522 | Protective effects of chicoric acid on LPS-induced endometritis in mice via inhibiting ferroptosis by Nrf2/HO-1 signal axis |
Chromium | 📋 | ✍ | ⛔ | | 34192590 | Zinc, selenium and chromium co-supplementation improves insulin resistance by preventing hepatic endoplasmic reticulum stress in diet-induced gestational diabetes rats |
Cinnamic Acid | 📋 | | | | 32767960 | Exploring the Molecular Mechanism of Cinnamic Acid-Mediated Cytotoxicity in Triple Negative MDA-MB-231 Breast Cancer Cells |
Citron | 📋 | | ⛔ | | 37860090 | In Vitro Assessment of The Bioactive Compounds and Anticancer Potential of Citrus medica Leaf Extract |
Coriander Essential Oil | 📋 | ✍ | ⛔ | | 26109513 | Alternative treatment of vaginal infections – in vitro antimicrobial and toxic effects of Coriandrum sativum L. and Thymus vulgaris L. essential oils |
Cumin | 📋 | | ⛔ | | 34201250 | Cumin Prevents 17β-Estradiol-Associated Breast Cancer in ACI Rats |
D-Limonene | 📋 | ✍ | ⛔ | | 37391551 | Combination of tamoxifen and D-limonene enhances therapeutic efficacy in breast cancer cells |
D-Mannose | 📋 | ✍ | ⛔ | | 33802263 | Complementary Medicine and Self-Care Strategies in Women with (Recurrent) Urinary Tract and Vaginal Infections: A Cross-Sectional Study on Use and Perceived Effectiveness in The Netherlands |
Dairy | 📋 | | | | 34368211 | Relationship Between Dairy Products Intake and Risk of Endometriosis: A Systematic Review and Dose-Response Meta-Analysis |
Diallyl Sulfide | 📋 | | | | 32819236 | Organosulphur Compounds Induce Apoptosis and Cell Cycle Arrest in Cervical Cancer Cells via Downregulation of HPV E6 and E7 Oncogenes |
Echinacea | 📋 | ✍ | ⛔ | | 32959676 | Echinacea Angustifolia DC Extract Induces Apoptosis and Cell Cycle Arrest and Synergizes with Paclitaxel in the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines |
Eleuthero | 📋 | ✍ | ⛔ | | 16619374 | Effect of a Combination of Extract From Several Plants on Cell-Mediated and Humoral Immunity of Patients With Advanced Ovarian Cancer |
Emu Oil | 📋 | ✍ | ⛔ | | 28691132 | Randomized phase II placebo-controlled study to evaluate the efficacy of topical pure emu oil for joint pain related to adjuvant aromatase inhibitor use in postmenopausal women with early breast cancer: JUST (Joints Under Study) |
Eucalyptus Essential Oil | 📋 | | ⛔ | | 22645627 | In Vitro Cytotoxic Potential of Essential Oils of Eucalyptus benthamii and Its Related Terpenes on Tumor Cell Lines |
Eucommia | 📋 | ✍ | ⛔ | | 33617969 | Effects of total flavonoids from Eucommia ulmoides Oliv. leaves on polycystic ovary syndrome with insulin resistance model rats induced by letrozole combined with a high-fat diet |
Fat | 📋 | | | | 36983810 | The Role of Dietary Fats in the Development and Treatment of Endometriosis |
Feverfew | 📋 | ✍ | ⛔ | | 16579729 | Antiproliferative Activities of Parthenolide and Golden Feverfew Extract Against Three Human Cancer Cell Lines |
Forskolin | 📋 | ✍ | ⛔ | | 35478276 | Inhibition of DDX3 and COX-2 by forskolin and evaluation of anti-proliferative, pro-apoptotic effects on cervical cancer cells: molecular modelling and in vitro approaches |
Geniposide | 📋 | | | | 33321605 | Evaluation of inhibitory effects of geniposide on a tumor model of human breast cancer based on 3D printed Cs/Gel hybrid scaffold |
Glucosamine | 📋 | ✍ | ⛔ | | 36462645 | Protective effect of glucosamine on zearalenone-induced reproductive toxicity and placental dysfunction in mice |
Glutathione | 📋 | ✍ | ⛔ | | 38253037 | Protective effect of glutathione administration on ovarian function in female rats with cyclophosphamide-induced ovarian damage |
Grape Seed Oil | 📋 | | ⛔ | | 32419817 | Comparing the Effect of Foot Massage with Grape Seed Oil and Sweet Almond Oil on Physiological Leg Edema in Primigravidae: A Randomized Clinical Trial |
Gymnema Sylvestre | 📋 | ✍ | ⛔ | | 36670996 | Anti-Tumor Potential of Gymnema sylvestre Saponin Rich Fraction on In Vitro Breast Cancer Cell Lines and In Vivo Tumor-Bearing Mouse Models |
Hemp Oil | 📋 | ✍ | ⛔ | | 37704445 | Prophylactic Effects of Hemp Seed Oil on Perimenopausal Depression: A Role of HPA Axis |
Horsetail Grass | 📋 | ✍ | ⛔ | | 35392596 | UHPLC-MS/MS-GNPS based phytochemical investigation of Equisetum arvense L. And evaluation of cytotoxicity against human melanoma and ovarian cancer cells |
Hypericin | 📋 | | | | 26865836 | Cytotoxic and Apoptogenic Effect of Hypericin, the Bioactive Component of Hypericum Perforatum on the MCF-7 Human Breast Cancer Cell Line |
Iron | 📋 | ✍ | ⛔ | | 36432476 | Iron Supplementation in Pregnancy and Risk of Gestational Diabetes: A Narrative Review |
Jasmine | 📋 | | ⛔ | | 34488594 | Antioxidant, Anti-Inflammatory and Cytotoxic Activities of Jasminum multiflorum (Burm. F.) Andrews Leaves towards MCF-7 Breast Cancer and HCT 116 Colorectal Cell Lines and Identification of Bioactive Metabolites |
Jasmine Essential Oil | 📋 | | | | 37129744 | Network pharmacology integrated with molecular docking reveals the anticancer mechanism of Jasminum sambac Linn. essential oil against human breast cancer and experimental validation by in vitro and in vivo studies |
Jujube | 📋 | | ⛔ | | 34237667 | Licorice (Glycyrrhiza spp.) and jujube (Ziziphus jujuba Mill.) formula for menopausal symptoms: Classical records, clinical evidence and experimental data |
Kiwifruit | 📋 | ✍ | ⛔ | | 34852177 | Actinidia chinensis Planch. root extract inhibits the proliferation, migration and invasion of breast cancer cells via the AKT/GSK-3β signaling pathway |
Knotweed | 📋 | ✍ | ⛔ | | 33381593 | Phenolic Compounds from Polygonum chinense Induce Growth Inhibition and Apoptosis of Cervical Cancer SiHa Cells |
Kombucha | 📋 | ✍ | ⛔ | | 34744740 | The Efficacy and Safety of Multiple Dose Regimens of Kudzu ( Pueraria lobata) Root Extract on Bone and Cartilage Turnover and Menopausal Symptoms |
L-Ornithine | 📋 | ✍ | ⛔ | | 32968187 | Ornithine and breast cancer: a matched case-control study |
L-Theanine | 📋 | ✍ | ⛔ | | 27612630 | Theanine from tea and its semi-synthetic derivative TBrC suppress human cervical cancer growth and migration by inhibiting EGFR/Met-Akt/NF-κB signaling |
Lauric Acid | 📋 | ✍ | | | 33140642 | Dietary Supplementation of Lauric Acid Alleviates the Irregular Estrous Cycle and the Impaired Metabolism and Thermogenesis in Female Mice Fed with High-Fat Diet (HFD) |
Lemon Balm Essential Oil | 📋 | ✍ | ⛔ | | 37998884 | Antifungal Activity and Type of Interaction of Melissa officinalis Essential Oil with Antimycotics against Biofilms of Multidrug-Resistant Candida Isolates from Vulvovaginal Mucosa |
Lemon Essential Oil | 📋 | ✍ | ⛔ | | 37743153 | The effect of aromatherapy massage with lemon and peppermint essential oil on menopausal symptoms: A double-blinded, randomized placebo controlled clinical trial |
Lemon Verbena | 📋 | | ⛔ | | 34070804 | Antitumor Potential of Lippia citriodora Essential Oil in Breast Tumor-Bearing Mice |
Lettuce | 📋 | | ⛔ | | 35889834 | Evaluation of the Effectiveness of Fermented Soybean-Lettuce Powder for Improving Menopausal Symptoms |
Long Pepper | 📋 | | ⛔ | | 37392181 | Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells |
Loquat | 📋 | ✍ | ⛔ | | 27087896 | Loquat (Eriobotrya japonica) leaf extract inhibits the growth of MDA-MB-231 tumors in nude mouse xenografts and invasion of MDA-MB-231 cells |
Lovage | 📋 | | ⛔ | | 34062080 | The effect of Apium graveolens L., Levisticum officinale and Calendula officinalis L. on cell viability, membrane integrity, steroidogenesis, and intercellular communication in mice Leydig cells in vitro |
Magnolia | 📋 | ✍ | ⛔ | | 35257639 | Long-term effects of a combination of isoflavones, agnus castus and magnolia extracts on climacteric symptoms and cardiometabolic risk profile in postmenopausal women |
Mandarin | 📋 | | | | 33105861 | Efficacy and Safety of Kudzu Flower-Mandarin Peel on Hot Flashes and Bone Markers in Women during the Menopausal Transition: A Randomized Controlled Trial |
Manganese | 📋 | ✍ | ⛔ | | 35414506 | Manganese Deficiency Promotes the Progression of Invasive Adenocarcinoma of the Cervix by Enhancing the Inflammatory Response |
Marjoram Essential Oil | 📋 | | ⛔ | | 22435409 | Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial |
Marshmallow Root | 📋 | | ⛔ | | 37121836 | The efficacy of complementary treatment with marshmallow (Althaea officinalis L.) on vulvovaginal candidiasis: A randomized double-blinded controlled clinical trial |
Mastic | 📋 | ✍ | ⛔ | | 38635559 | Pistacia lentiscus L. revealed in vitro anti-proliferative activity on MCF-7 breast cancer cells and in vivo anti-mammary cancer effect on C57BL/6 mice through necrosis, anti-inflammatory and antioxidant enhancements |
Matcha Tea | 📋 | | | | 37737883 | Effects of matcha tea extract on cell viability and estrogen receptor-β expression on MCF-7 breast cancer cells |
Milk | 📋 | | ⛔ | | 34662821 | Investigation of the supportive therapy potential of propolis extract and Lactobacillus acidophilus LA-5 milk combination against breast cancer in mice |
Minerals | 📋 | | | | 37752229 | The association between dietary mineral intake and the risk of preeclampsia in Chinese pregnant women: a matched case-control study |
Neem Oil | 📋 | ✍ | ⛔ | | 31080481 | Potential of Regular Consumption of Cameroonian Neem ( Azadirachta indica L.) Oil for Prevention of the 7,12-Dimethylbenz(a)anthracene-Induced Breast Cancer in High-Fat/Sucrose-Fed Wistar Rats |
Neohesperidin | 📋 | | | | 23285810 | Neohesperidin induces cellular apoptosis in human breast adenocarcinoma MDA-MB-231 cells via activating the Bcl-2/Bax-mediated signaling pathway |
Nootkatone | 📋 | | | | 35631492 | Impairment of Glucose Metabolism and Suppression of Stemness in MCF-7/SC Human Breast Cancer Stem Cells by Nootkatone |
Nuts | 📋 | | ⛔ | | 35345969 | Soy foods and nuts consumption during early pregnancy are associated with decreased risk of gestational diabetes mellitus: a prospective cohort study |
Oak Bark | 📋 | ✍ | ⛔ | | 34634366 | The anticancer activity of root extract from Quercus acutissima Carruth. Via regulating apoptosis and autophagy in breast cancer cells |
Oleic Acid | 📋 | | ⛔ | | 38001668 | Oleic Acid Exhibits Anti-Proliferative and Anti-Invasive Activities via the PTEN/AKT/mTOR Pathway in Endometrial Cancer |
Orange Essential Oil | 📋 | ✍ | ⛔ | | 36457653 | Effects of Aromatherapy With Citrus Aurantium Lavender on Sexual Function of Postmenopausal Women: A Randomized Controlled Trial |
Oregano | 📋 | ✍ | ⛔ | | 26907089 | Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model |
Osmanthus | 📋 | ✍ | ⛔ | | 23255955 | Pomolic acid induces apoptosis in SK-OV-3 human ovarian adenocarcinoma cells through the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways |
Oyster Mushrooms | 📋 | | ⛔ | | 20921274 | Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells |
Pantethine | 📋 | ✍ | ⛔ | | 2359503 | [Evaluation of the cholesterol-lowering effectiveness of pantethine in women in perimenopausal age] |
Peas | 📋 | | ⛔ | | 36547584 | A New Approach for the Treatment of Recurrent Vulvovaginal Candidiasis with a Combination of Pea Protein, Grape Seed Extract, and Lactic Acid Assessed In Vivo |
Pecan | 📋 | | ⛔ | | 28807853 | Aqueous extract from pecan nut [Carya illinoinensis (Wangenh) C. Koch] shell show activity against breast cancer cell line MCF-7 and Ehrlich ascites tumor in Balb-C mice |
Pelargonidin | 📋 | | | | 37255368 | Protective Effects of Pelargonidin against DMBA-Induced Mammary Tumorigenesis in BALB/c Mice through Reduced Oxidative Stress and Lipid Anomalies |
Peppermint Essential Oil | 📋 | ✍ | ⛔ | | 37743153 | The effect of aromatherapy massage with lemon and peppermint essential oil on menopausal symptoms: A double-blinded, randomized placebo controlled clinical trial |
Pine Needle Essential Oil | 📋 | ✍ | ⛔ | | 29115548 | Frankincense, pine needle and geranium essential oils suppress tumor progression through the regulation of the AMPK/mTOR pathway in breast cancer |
Postbiotics | 📋 | | | | 38463778 | Vaginal microbiota: Potential targets for vulvovaginal candidiasis infection |
Prickly Pear | 📋 | | ⛔ | | 34622044 | Comparative study between in vivo- and in vitro-derived extracts of cactus ( Opuntis ficus-indica L. Mill) against prostate and mammary cancer cell lines |
Quercitrin | 📋 | | | | 37321077 | Quercitrin alleviates lipid metabolism disorder in polycystic ovary syndrome-insulin resistance by upregulating PM20D1 in the PI3K/Akt pathway |
Rapeseed Oil | 📋 | ✍ | | | 33514384 | The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a randomized controlled trial |
Red Yeast Rice | 📋 | ✍ | ⛔ | | 33250768 | Simvastatin Suppresses Human Breast Cancer Cell Invasion by Decreasing the Expression of Pituitary Tumor-Transforming Gene 1 |
Rhodiola | 📋 | ✍ | ⛔ | | 16619374 | Effect of a Combination of Extract From Several Plants on Cell-Mediated and Humoral Immunity of Patients With Advanced Ovarian Cancer |
Rosemary Essential Oil | 📋 | ✍ | ⛔ | | 28042599 | Assessment of Cytotoxic Activity of Rosemary ( Rosmarinus officinalis L.), Turmeric ( Curcuma longa L.), and Ginger ( Zingiber officinale R.) Essential Oils in Cervical Cancer Cells (HeLa) |
Sage Essential Oil | 📋 | | ⛔ | | 37612717 | Effect of Salvia officinalis scent on postmenopausal women's sexual function and satisfaction: a randomized controlled trial |
Salt | 📋 | | ⛔ | | 34084229 | The effect of salt supplements on thyroid hormones and quality of pregnancy in female hypothyroid rats |
Scutellarein | 📋 | | | | 34350670 | Scutellarein induces apoptosis and inhibits proliferation, migration, and invasion in ovarian cancer via inhibition of EZH2/FOXO1 signaling |
Sesame Oil | 📋 | | ⛔ | | 36810739 | Ameliorative effect of sesame oil on experimentally induced polycystic ovary syndrome: A cross-link between XBP-1/PPAR-1, regulatory proteins for lipogenesis/steroids |
Sesamolin | 📋 | | | | 38698330 | Sesamolin serves as an MYH14 inhibitor to sensitize endometrial cancer to chemotherapy and endocrine therapy via suppressing MYH9/GSK3β/β-catenin signaling |
Shallot | 📋 | | ⛔ | | 36331692 | Screening of Anti-carcinogenic Properties of Phytocompounds from Allium ascalonicum for Treating Breast Cancer Through In Silico and In Vitro Approaches |
Star Fuit | 📋 | | ⛔ | | 26203774 | The antidiabetic compound 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from Averrhoa carambola L., demonstrates significant antitumor potential against human breast cancer cells |
Sunflower | 📋 | | ⛔ | | 37324929 | Effectiveness of combined seeds (pumpkin, sunflower, sesame, flaxseed): As adjacent therapy to treat polycystic ovary syndrome in females |
Sweet Potato | 📋 | | ⛔ | | 34025021 | Lipid-soluble polyphenols from sweet potato exert antitumor activity and enhance chemosensitivity in breast cancer |
Taro Root | 📋 | | ⛔ | | 34376983 | An Extract of Taro ( Colocasia esculenta) Mediates Potent Inhibitory Actions on Metastatic and Cancer Stem Cells by Tumor Cell-Autonomous and Immune-Dependent Mechanisms |
Toothache Plant | 📋 | | | | 34468763 | Spilanthol as a promising antifungal alkylamide for the treatment of vulvovaginal candidiasis |
Vitamin B Complex | 📋 | | ⛔ | | 15790610 | Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin: a randomized trial |
Vitamin B5 | 📋 | ✍ | ⛔ | | 27900284 | Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism |
Vitamin B7 | 📋 | ✍ | ⛔ | | 36432448 | Biotin Enhances Testosterone Production in Mice and Their Testis-Derived Cells |
Vitamin K | 📋 | ✍ | ⛔ | | 36501073 | Relationship between Vitamin Intake and Resilience Based on Sex in Middle-Aged and Older Japanese Adults: Results of the Shika Study |
Vitamin K1 | 📋 | ✍ | ⛔ | | 28733110 | A role of alpha-tocopherol and phylloquinone in the modulation of uterine contractility and reproductive function in mouse models |
Wasabi | 📋 | | ⛔ | | 36689027 | Anti-tumor effect of Wasabi component, 6-(methylsulfinyl) hexyl isothiocyanate, against endometrial carcinoma cells |
Watercress | 📋 | ✍ | ⛔ | | 36351033 | Nasturtium officinale L. and metformin alleviate the estradiol -induced polycystic ovary syndrome with synergistic effects through modulation of Bax/Bcl-2/p53/caspase-3 signaling pathway and anti-inflammatory and anti-oxidative effects |
Yerba Mate | 📋 | ✍ | ⛔ | | 34858179 | Yerba Mate Modulates Tumor Cells Functions Involved in Metastasis in Breast Cancer Models |
Zingerone | 📋 | | | | 33544516 | Zingerone improves the immune responses in an animal model of breast cancer |